Multiple Adipokines Predict Dementia Severity as Measured by δ: Replication Across Biofluids and Cohorts

DR Royall, RF Palmer - Journal of Alzheimer's Disease, 2023 - content.iospress.com
Background: We have explored dementia's blood-based protein biomarkers in the Texas
Alzheimer's Research and Care Consortium (TARCC) study. Among them are adipokines …

Association between plasma leptin and estrogen in female patients of amnestic mild cognitive impairment

Y Xing, J Liu, J Xu, L Yin, L Wang, J Li, Z Yu… - Disease …, 2015 - Wiley Online Library
Increasing evidences suggested the association between leptin and cognitive functions.
Estrogen is an important factor that regulates the production and metabolism of leptin …

Effects of gender and other confounding factors on leptin concentrations in Alzheimer's disease: evidence from the combined analysis of 27 case-control studies

F Zhou, S Chen - Journal of Alzheimer's Disease, 2018 - content.iospress.com
Leptin, as a link between fat mass and the brain, has been reported to be associated with
gender. The gender differences in leptin levels between Alzheimer's disease (AD) and …

Plasma leptin concentration and sympathetic nervous activity in older adults with physical dysfunction

K Shibasaki, S Yamada, M Akishita… - Journal of the …, 2018 - academic.oup.com
Context Previous research has shown a positive relationship between plasma leptin and
sympathetic nervous activity. High plasma leptin activate inflammatory cytokines and lead to …

Cognitive enhancers (Nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. Disease-modifying drugs. Update 2014

W Froestl, A Pfeifer, A Muhs - Journal of Alzheimer's Disease, 2014 - content.iospress.com
Scientists working in the field of Alzheimer's disease and, in particular, cognitive enhancers,
are very productive. The review “Drugs interacting with Targets other than Receptors or …

[HTML][HTML] The cerebellum and premenstrual dysphoric disorder

AJ Rapkin, SM Berman, ED London - AIMS neuroscience, 2014 - ncbi.nlm.nih.gov
The cerebellum constitutes ten percent of brain volume and contains the majority of brain
neurons. Although it was historically viewed primarily as processing motoric computations …

Association of Adipokines with Alzheimer's Disease in a Chinese Cohort

CC Liu, QH Wang, JY Xin, YH Liu… - Journal of …, 2023 - content.iospress.com
Background: The correlation between plasma adipose factor levels and Alzheimer's patients
is not entirely clear. Objective: We aimed to investigate associations between AD and …

U-shaped relationship between serum leptin concentration and cognitive performance in older asian adults

C Annweiler, GT Duval, CY Cheng, TY Wong… - Nutrients, 2019 - mdpi.com
The role of leptin (a hormone related to fat mass) in cognition remains equivocal. Our
objective was to investigate the relationship between circulating leptin concentration and …

Effect of apolipoprotein E (APO E) polymorphism on leptin in Alzheimer's disease

R Agarwal, P Talwar, SS Kushwaha… - Annals of Indian …, 2015 - journals.lww.com
Background: Leptin, a 16 kDa peptide hormone synthesized and secreted specifically from
white adipose cells protects neurons against amyloid β-induced toxicity, by increasing …

Neuroplasticity: the critical issue for Alzheimer's disease and links to obesity and depression

JW Ashford - The American Journal of Geriatric Psychiatry, 2023 - Am Assoc Geria Psych
In their paper, Ly et al. link obesity, Alzheimer's disease (AD), and depression, with the
consideration that there are neuroinflammatory mechanisms linking these conditions, and …