Chronic hepatitis B is a major health problem worldwide, with more than 250 million chronic
carriers. Hepatitis B virus interferes with the host innate immune system so as to evade …

Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection, has become a global public health crisis …

TRIM5γ, together with TRIM31, has been shown to promote HBx ubiquitination and
degradation. This study aimed to explore whether a patient with HCC (hepatic cell …

Hepatitis B virus (HBV) infection is still a serious public health problem worldwide. Antiviral
therapies such as interferon and nucleos (t) ide analogs efficiently control HBV replication …

Ubiquitination is a key mechanism for post-translational protein modification, affecting
protein localization, metabolism, degradation and various cellular physiological processes …

Hepatitis B virus (HBV) infection remains a major public health concern worldwide, with
approximately 296 million individuals chronically infected. The HBV-encoded X protein …

Objective Baicalin, which is a key bioactive constituent obtained from Scutellaria
baicalensis, has been utilized in traditional Chinese medicine for many centuries. Although it …

The worldwide impact of liver diseases is increasing steadily, with a consistent upswing
evidenced in incidence and mortality rates. Chronic liver diseases (CLDs) refer to the liver …

Tripartite motif (TRIM) proteins, comprising a family of over 100 members with conserved
motifs, exhibit diverse biological functions. Several TRIM proteins influence viral infections …

As humanity begins to venture further into space, approaches to better protect astronauts
from the hazards found in space need to be developed. One particular hazard of concern is …