As humanity begins to venture further into space, approaches to better protect astronauts
from the hazards found in space need to be developed. One particular hazard of concern is …

Background: The Tripartite motif (TRIM) family includes more than 80 distinct human genes.
Their function has been implicated in regulating important cellular processes, including …

Interferons (IFNs) represent a group of proteins with notable antiviral capabilities. Recently,
the discovery of type IV IFN, ie IFN-υ has created a new avenue for research on class II …

Human hepatitis B virus (HBV) infection is the major cause of acute and chronic hepatitis B,
liver cirrhosis, and hepatocellular carcinoma. Although the application of prophylactic …

Functional cure for chronic hepatitis B (CHB) remains challenging due to the lack of direct
intervention methods for hepatic inflammation. Multi‐omics research offers a promising …

As the key component of host innate antiviral immunity, type I interferons (IFN‐Is) exert
multiple antiviral effects by inducing hundreds of IFN‐stimulated genes. However, the …

Hepatitis B virus is one of the leading causes behind the neoplastic transformation of liver
tissue and associated mortality. Despite the availability of many therapies and vaccines, the …

Infection with the hepatitis B virus (HBV) is still a major global health threat as 250 million
people worldwide continue to be chronically infected with the virus. While patients may be …

The disease caused by hepatitis B virus (HBV) infection is a universal and important health
issue that troubles human beings. According to WHO (World Health Organization) estimates …

HBV 感染与肝硬化, 肝癌及肝衰竭等不良事件密切相关, 严重威胁人类健康.
聚乙二醇干扰素是治疗慢性乙型肝炎不可或缺的药物, 干扰素刺激基因与多种病毒感染相关 …