Aminoacyl-tRNA synthetases (ARSs) are essential enzymes for protein synthesis with
evolutionarily conserved enzymatic mechanisms. Despite their similarity across organisms …

Mutations in TP53, the gene that encodes the tumour suppressor p53, are found in 50% of
human cancers, and increased levels of its negative regulators MDM2 and MDM4 (also …

Aminoacylation of transfer RNAs establishes the rules of the genetic code. The reactions are
catalyzed by an ancient group of 20 enzymes (one for each amino acid) known as …

Over the past decade, the identification of cancer-associated factors has been a subject of
primary interest not only for understanding the basic mechanisms of tumorigenesis but also …

Aminoacyl-tRNA synthetases (ARSs) are a family of evolutionarily conserved housekeeping
enzymes used for protein synthesis that have pivotal roles in the ligation of tRNA with their …

Arare case of cardiac malignant fibrous histiocytoma (MFH) is reported. A55-year-old
womancomplained of palpitation due to atrial fibrillation. Echocardiography, magnetic …

Although aminoacyl-tRNA synthetases (ARSs) and ARS-interacting multi-functional proteins
(AIMPs) have long been recognized as housekeeping proteins, evidence indicating that they …

Double minutes (dmin), the cytogenetic hallmark of genomic amplification, are found in∼
1% of karyotypically abnormal acute myeloid leukemias (AML) and myelodysplastic …

Background and Aims Identifying malignant biliary strictures using endobiliary brushing
cytology specimens is important for treatment decision-making and prognosis prediction …

The NFAR gene (nuclear factor associated with dsRNA) encodes a putative transcription-
associated factor that we have shown is a substrate for the interferon-inducible, dsRNA …