Isolated growth hormone deficiency

LM Hernández, PDK Lee, C Camacho-Hübner - Pituitary, 2007 - Springer
Isolated growth hormone deficiency (IGHD) represents conditions of GH deficiency that are
not necessarily associated with other pituitary hormone deficiencies or with an organic …

[HTML][HTML] Pituitary stalk interruption syndrome: diagnostic delay and sensitivity of the auxological criteria of the growth hormone research society

G Gascoin-Lachambre, R Brauner, L Duche… - PloS one, 2011 - journals.plos.org
Objectives To study the diagnostic delay for pituitary stalk interruption syndrome (PSIS) with
growth hormone deficiency (GHD) and the sensitivity of the auxological criteria of the Growth …

Seven years of safety and efficacy of the recombinant human growth hormone Omnitrope® in the treatment of growth hormone deficient children: results of a phase III …

T Romer, P Saenger, F Peter, M Walczak… - Hormone Research in …, 2009 - karger.com
Aim: This phase III clinical study in growth hormone deficiency (GHD) children with growth
retardation was designed to compare efficacy and safety of Omnitrope® with Genotropin® …

Pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient children

SF Kemp, PJ Fielder, KM Attie… - The Journal of …, 2004 - academic.oup.com
Long-term GH replacement therapy is indicated for children with growth failure due to GH
deficiency (GHD). We evaluated the feasibility of administering a long-acting GH preparation …

Evaluation of pituitary function after traumatic brain injury in childhood

SN Khadr, PM Crofton, PA Jones… - Clinical …, 2010 - Wiley Online Library
Objectives Post‐traumatic hypopituitarism is well described amongst adult traumatic brain
injury (TBI) survivors. We aimed to determine the prevalence and clinical significance of …

[HTML][HTML] Whole exome sequencing uncovered the genetic architecture of growth hormone deficiency patients

C Yu, B Xie, Z Zhao, S Zhao, L Liu, X Cheng… - Frontiers in …, 2021 - frontiersin.org
Purpose Congenital growth hormone deficiency (GHD) is a rare and etiologically
heterogeneous disease. We aim to screen disease-causing mutations of GHD in a relatively …

[HTML][HTML] Endocrinopathies in survivors of childhood neoplasia

N Barnes, W Chemaitilly - Frontiers in Pediatrics, 2014 - frontiersin.org
Advancements in cancer treatments have increased the number of survivors of childhood
cancers. Endocrinopathies are common complications following cancer therapy and may …

Growth hormone therapy and quality of life in adults and children

DJ Radcliffe, JS Pliskin, JB Silvers, L Cuttler - Pharmacoeconomics, 2004 - Springer
A fundamental goal of growth hormone (GH) treatment for both adults and children is
improvement in quality of life (QOL). Assessments of the therapeutic role of GH depend on …

Prospective investigation of anterior pituitary function in the acute phase and 12 months after pediatric traumatic brain injury

H Ulutabanca, N Hatipoglu, F Tanriverdi… - Child's nervous …, 2014 - Springer
Purpose Although head trauma is common in childhood, there is no enough prospective
study investigating both acute phase and 12 months after injury. Therefore, a prospective …

Utility of free IGF-I measurements

J Frystyk - Pituitary, 2007 - Springer
For nearly 30 years, the endogenous bioactivity of insulin-like growth factor I (IGF-I) has
been estimated by its circulating concentrations of immunoreactive IGF-I, obtained after …