[HTML][HTML] Flavonoids—Natural gifts to promote health and longevity

X Fan, Z Fan, Z Yang, T Huang, Y Tong… - International Journal of …, 2022 - mdpi.com
The aging of mammals is accompanied by the progressive atrophy of tissues and organs
and the accumulation of random damage to macromolecular DNA, protein, and lipids …

[HTML][HTML] Mechanism of dihydromyricetin on inflammatory diseases

Y Sun, S Liu, S Yang, C Chen, Y Yang, M Lin… - Frontiers in …, 2022 - frontiersin.org
Inflammation plays a crucial role in a variety of diseases, including diabetes, arthritis,
asthma, Alzheimer's disease (AD), acute cerebral stroke, cancer, hypertension, and …

[HTML][HTML] TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer's disease mice

Y Wang, Y Lin, L Wang, H Zhan, X Luo, Y Zeng… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Triggering receptor expressed on myeloid cells 2 (TREM2) has been shown with a
neuroprotective function against inflammation and neuronal injury in Alzheimer's disease …

Nanoassemblies derived from natural flavonoid compounds as new antioxidant oral preparations for targeted inflammatory bowel disease therapy

N Tang, Z Ding, S Zhang, D Luo, X Liu… - Advanced Functional …, 2023 - Wiley Online Library
Possessing the largest surface area of mucosa in the body, the gastrointestinal (GI) tract can
easily sufferfrom inflammatory damage under various adverse external exposures, resulting …

Dihydromyricetin alleviates doxorubicin-induced cardiotoxicity by inhibiting NLRP3 inflammasome through activation of SIRT1

Z Sun, W Lu, N Lin, H Lin, J Zhang, T Ni, L Meng… - Biochemical …, 2020 - Elsevier
Doxorubicin (DOX) is a powerful anthracycline antineoplastic drug whose clinical
application is limited by serious cardiotoxic side effects. Dihydromyricetin (DHM), a flavonoid …

A comprehensive review of vine tea: Origin, research on Materia Medica, phytochemistry and pharmacology

T Zeng, Y Song, S Qi, R Zhang, L Xu, P Xiao - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Vine tea is a popular folk tea that has been consumed in
China for more than 1200 years. It is often used in ethnic medicine by ethnic groups in …

Dihydromyricetin attenuates D-galactose-induced brain aging of mice via inhibiting oxidative stress and neuroinflammation

J Qian, X Wang, J Cao, W Zhang, C Lu, X Chen - Neuroscience Letters, 2021 - Elsevier
Aging-related especially brain aging-related diseases are heavy health care burdens
worldwide. Natural products with antioxidant and anti-inflammatory properties have been …

[HTML][HTML] Recent update on application of dihydromyricetin in metabolic related diseases

Y Wang, J Wang, H Xiang, P Ding, T Wu, G Ji - Biomedicine & …, 2022 - Elsevier
As a new type of natural flavonoids, dihydromyricetin (DMY) has attracted more and more
attention. It has a series of pharmacological effects, such as anti-inflammatory, anti-tumor …

[HTML][HTML] Dihydromyricetin enhances intestinal antioxidant capacity of growing-finishing pigs by activating ERK/Nrf2/HO-1 signaling pathway

C Wei, X Chen, D Chen, B Yu, P Zheng, J He, H Chen… - Antioxidants, 2022 - mdpi.com
Oxidative stress is one of the main factors affecting animal health and reducing performance.
The small intestine is the primary site of free-radical attacks. Dihydromyricetin (DHM) is a …

Dihydromyricetin protects against Doxorubicin-induced cardiotoxicity through activation of AMPK/mTOR pathway

X Li, X Wang, B Wang, W Chi, Z Li, M Zhang, Y Shen… - Phytomedicine, 2022 - Elsevier
Background Doxorubicin (DOX) is a highly effective broad-spectrum antitumor agent, but its
clinical administration is limited by self-induced cardiotoxicity. Dihydromyricetin (DHM) is a …