Biological hypotheses, risk factors, and biomarkers of schizophrenia

Z Fišar - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

[HTML][HTML] The Effects of Andrographis paniculata (Burm.F.) Wall. Ex Nees and Andrographolide on Neuroinflammation in the Treatment of Neurodegenerative …

F Bosco, S Ruga, R Citraro, A Leo, L Guarnieri… - Nutrients, 2023 - mdpi.com
Neurodegenerative diseases (NDs) affect millions of people worldwide, and to date,
Alzheimer's and Parkinson's diseases are the most common NDs. Of the many risk factors …

Neurodevelopmental toxicity induced by PM2. 5 Exposure and its possible role in Neurodegenerative and mental disorders

X Liu, J Huang, C Song, T Zhang… - Human & …, 2023 - journals.sagepub.com
Recent extensive evidence suggests that ambient fine particulate matter (PM2. 5, with an
aerodynamic diameter≤ 2.5 μm) may be neurotoxic to the brain and cause central nervous …

[HTML][HTML] Is it time for a paradigm shift in the treatment of schizophrenia? the use of inflammation-reducing and neuroprotective Drugs—A review

A Messina, C Concerto, A Rodolico, A Petralia… - Brain Sciences, 2023 - mdpi.com
Comprehending the pathogenesis of schizophrenia represents a challenge for global
mental health. To date, although it is evident that alterations in dopaminergic, serotonergic …

[HTML][HTML] Cytokine imbalance as a biomarker of treatment-resistant schizophrenia

NA Shnayder, AK Khasanova, AI Strelnik… - International Journal of …, 2022 - mdpi.com
Treatment-resistant schizophrenia (TRS) is an important and unresolved problem in
biological and clinical psychiatry. Approximately 30% of cases of schizophrenia (Sch) are …

The Molecular Basis of Wnt/β‐Catenin Signaling Pathways in Neurodegenerative Diseases

AA Anand, M Khan, MV, D Kar - International Journal of Cell …, 2023 - Wiley Online Library
Defective Wnt signaling is found to be associated with various neurodegenerative diseases.
In the canonical pathway, the Frizzled receptor (Fzd) and the lipoprotein receptor‐related …

[HTML][HTML] Short-chain fatty acids in patients with schizophrenia and ultra-high risk population

H Peng, L Ouyang, D Li, Z Li, L Yuan, L Fan… - Frontiers in …, 2022 - frontiersin.org
Background Individuals who experience the prodromal phase of schizophrenia (SCZ), a
common and complex psychiatric disorder, are referred to as ultra-high-risk (UHR) …

Neuroinflammation: the abused concept

E Galea, MB Graeber - ASN neuro, 2023 - journals.sagepub.com
Scientific progress requires the relentless correction of errors and refinement of hypotheses.
Clarity of terminology is essential for clarity of thought and proper experimental interrogation …

[HTML][HTML] Antipsychotic effect of diosgenin in ketamine-induced murine model of schizophrenia: Involvement of oxidative stress and cholinergic transmission

B Ben-Azu, OG Adebayo, AR Fokoua… - IBRO Neuroscience …, 2024 - Elsevier
A decrease in the levels of antioxidant arsenals exacerbate generation of reactive
oxygen/nitrogen species, leading to neurochemical dysfunction, with significant impact on …

[HTML][HTML] Immunological protein profiling of first-episode psychosis patients identifies CSF and blood biomarkers correlating with disease severity

F Eren, L Schwieler, F Orhan, A Malmqvist… - Brain, behavior, and …, 2023 - Elsevier
Abstract Background and Hypothesis Immune activation is suggested to play an important
role in psychosis. In this study, a large number of immune-related proteins were analyzed to …