Heart failure with preserved ejection fraction: a comprehensive review and update of diagnosis, pathophysiology, treatment, and perioperative implications

PS Pagel, JN Tawil, BT Boettcher, DA Izquierdo… - Journal of cardiothoracic …, 2021 - Elsevier
Almost three-quarters of all heart failure patients who are older than 65 have heart failure
with preserved ejection fraction (HFpEF). The proportion and hospitalization rate of patients …

Mechanical function of the left atrium: new insights based on analysis of pressure–volume relations and Doppler echocardiography

PS Pagel, F Kehl, M Gare, DA Hettrick… - The Journal of the …, 2003 - pubs.asahq.org
THE left atrium (LA) serves three major roles that exert a profound effect on left ventricular
(LV) filling and overall cardiovascular performance. The LA is a contractile chamber that …

Left atrial systolic and diastolic dysfunction in heart failure with normal left ventricular ejection fraction

DA Morris, M Gailani, AV Pérez, F Blaschke… - Journal of the American …, 2011 - Elsevier
Background The authors hypothesized that in patients with heart failure with normal left
ventricular (LV) ejection fraction (HFNEF), the same fibrotic processes that affect the …

LA mechanics in decompensated heart failure: insights from strain echocardiography with invasive hemodynamics

S Deferm, P Martens, FH Verbrugge, PB Bertrand… - Cardiovascular …, 2020 - jacc.org
Objectives The aim of this study was to assess the effect of congestion and decongestive
therapy on left atrial (LA) mechanics and to determine the relationship between LA …

MRI and echocardiographic assessment of the diastolic dysfunction of normal aging: altered LV pressure decline or load?

PS Hees, JL Fleg, SJ Dong… - American Journal of …, 2004 - journals.physiology.org
Changes in diastolic indexes during normal aging, including reduced early filling velocity
(E), lengthened E deceleration time (DT), augmented late filling (A), and prolonged …

Left atrial strain at different stages of myxomatous mitral valve disease in dogs

K Nakamura, S Kawamoto, T Osuga… - Journal of veterinary …, 2017 - Wiley Online Library
Background Decreased function of the left atrium (LA) is a useful prognostic indicator in
dogs with myxomatous mitral valve disease (MMVD). In humans, LA strain is a novel severity …

Left atrial dysfunction as an independent correlate of heart failure symptoms in patients with severe aortic stenosis and preserved left ventricular ejection fraction

AD Mateescu, A Călin, CC Beladan, M Roşca… - Journal of the American …, 2019 - Elsevier
Background Data regarding the contribution of left atrial (LA) dysfunction to the occurrence
of heart failure in patients with severe aortic stenosis (AS) are scarce. The aim of this study …

Impaired left atrial systolic function and inter-atrial dyssynchrony may contribute to symptoms of heart failure with preserved left ventricular ejection fraction: A …

S Liu, Z Guan, X Zheng, P Meng, Y Wang, Y Li… - International Journal of …, 2018 - Elsevier
Aims To assess LA diastolic and systolic function and atrial dyssynchrony in patients with
heart failure with preserved ejection fraction (HFpEF) and to examine whether LA …

Prognostic Implications of Left Atrial Strain in Bicuspid Aortic Valve With Chronic Aortic Regurgitation

YT Tan, YM Li, WH Deng, RZ Zhang… - Journal of the …, 2024 - Am Heart Assoc
Background Left atrial reservoir strain (LARS) is a novel imaging biomarker of left ventricular
diastolic dysfunction. This study aimed to examine the prognostic implications of LARS in …

Improvement of afterload mismatch of left atrial booster pump function with positive inotropic agent

H Sakai, H Kunichika, K Murata, K Seki… - Journal of the American …, 2001 - jacc.org
OBJECTIVES The objective of this study was to examine the hypothesis that a positive
inotropic agent improves left ventricular (LV) filling during left atrial (LA) contraction in the …