Real-world data: a brief review of the methods, applications, challenges and opportunities

F Liu, D Panagiotakos - BMC Medical Research Methodology, 2022 - Springer
Background The increased adoption of the internet, social media, wearable devices, e-
health services, and other technology-driven services in medicine and healthcare has led to …

[HTML][HTML] Biologic drug survival in psoriasis: a systematic review & comparative meta-analysis

AI Mourad, R Gniadecki - Frontiers in Medicine, 2021 - frontiersin.org
Drug survival studies have been utilized to evaluate the real-world effectiveness of biologics
used in psoriasis. However, the increasing volume of drug survival data suffers from large …

Biologic drug survival rates in the era of anti‐interleukin‐17 antibodies: a time‐period‐adjusted registry analysis

T Graier, W Salmhofer, C Jonak… - British Journal of …, 2021 - academic.oup.com
Background Drug survival rates reflect efficacy and safety and may be influenced by the
availability of alternative treatment options. Little is known about time‐dependent drug …

Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways

A Liu, B Zhang, W Zhao, Y Tu, Q Wang, J Li - Bioengineered, 2021 - Taylor & Francis
Psoriasis is a chronic inflammatory skin disease that affects approximately 2% of worldwide
population, and causing long-term troubles to the patients. Therefore, it is urgent to develop …

Galangin ameliorates Imiquimod-Induced psoriasis-like skin inflammation in BALB/c mice via down regulating NF-κB and activation of Nrf2 signaling pathways

R Sangaraju, S Alavala, N Nalban, MK Jerald… - International …, 2021 - Elsevier
Psoriasis is a most common chronic autoimmune-arbitrated cutaneous inflammatory skin
disorder by unclear pathogenesis. In this current study we demonstrated the effect of …

Adherence and persistence to biological drugs for psoriasis: systematic review with meta-analysis

E Piragine, D Petri, A Martelli, A Janowska… - Journal of Clinical …, 2022 - mdpi.com
Despite the large number of biologics currently available for moderate-to-severe psoriasis,
poor adherence and persistence to therapy represent the main issues for both the clinical …

Drug Survival of IL-17 and IL-23 Inhibitors for Psoriasis: A Systematic Review and Meta-Analysis

SE Thomas, L Barenbrug, G Hannink, MMB Seyger… - Drugs, 2024 - Springer
Abstract Background and Objective The most recently approved biologics for moderate-to-
severe psoriasis are the interleukin (IL)-17 and IL-23 inhibitors. Drug survival is a frequently …

Patient preference for biologic treatments of psoriasis in Japan

Y Tada, K Ishii, J Kimura, K Hanada… - The Journal of …, 2019 - Wiley Online Library
Psoriasis is a chronic autoimmune disease affecting skin which may also manifest in nails
and joints. Several biologic treatments have been approved in Japan for psoriasis. Each …

Protective effects of ambroxol in psoriasis like skin inflammation: Exploration of possible mechanisms

S Sunkari, S Thatikonda, V Pooladanda… - International …, 2019 - Elsevier
The purpose of this study was to investigate the protective effects of ambroxol in psoriasis-
like skin inflammation both in vitro and in vivo and delineate the molecular mechanism of …

Treatment patterns, healthcare resource utilization, and costs in patients with moderate‐to‐severe psoriasis treated with systemic therapy in Japan: A retrospective …

Y Tada, H Kim, D Spanopoulos… - The Journal of …, 2022 - Wiley Online Library
The real‐world treatment landscape for patients with moderate‐to‐severe psoriasis
receiving systemic therapies in Japan is not well understood. This study describes the …