Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction

M Maccarrone, B Barboni, A Paradisi… - Journal of Cell …, 2005 - journals.biologists.com
Anandamide (AEA) is the endogenous ligand of cannabinoid (CB) receptors, and as such it
plays several central and peripheral activities. Regulation of female fertility by AEA has …

[HTML][HTML] Genetic engineering of animals: ethical issues, including welfare concerns

EH Ormandy, J Dale, G Griffin - The Canadian Veterinary Journal, 2011 - ncbi.nlm.nih.gov
The genetic engineering of animals has increased significantly in recent years, and the use
of this technology brings with it ethical issues, some of which relate to animal welfare …

CB2 receptors in reproduction

M Maccarrone - British journal of pharmacology, 2008 - Wiley Online Library
Cannabinoids have been always identified as harmful drugs because of their negative
effects on male and female reproduction. The discovery of the 'endocannabinoid system …

Human CD55 expression blocks hyperacute rejection and restricts complement activation in Gal knockout cardiac xenografts

CGA McGregor, D Ricci, N Miyagi… - …, 2012 - journals.lww.com
Background. Transgenic expression of human complement regulatory proteins reduces the
frequency of hyperacute rejection (HAR) in Gal-positive cardiac xenotransplantation. In this …

Prospects for xenotransplantation

JS Logan - Current Opinion in Immunology, 2000 - Elsevier
Pig-to-primate organ survival has been extended from a few minutes to weeks and
occasionally months, following the development of transgenic pigs that express human …

Phenotyping of transgenic cloned piglets

DB Carter, L Lai, KW Park, M Samuel… - Cloning & Stem …, 2002 - liebertpub.com
Numerous reports list the abnormalities obtained from cloning sheep and cattle. To date, few
reports provide detailed information regarding the overall health status and performance …

Study of full-length porcine endogenous retrovirus genomes with envelope gene polymorphism in a specific-pathogen-free Large White swine herd

S Bösch, C Arnauld, A Jestin - Journal of Virology, 2000 - Am Soc Microbiol
ABSTRACT Specific-pathogen-free (SPF) swine appear to be the most appropriate
candidate for pig to human xenotransplantation. Still, the risk of endogenous retrovirus …

Hematologic and biochemical reference intervals for 1‐month‐old specific‐pathogen‐free Landrace pigs

C Li, F Wang, R Li, M Ishfaq, H Chen… - Veterinary Clinical …, 2021 - Wiley Online Library
Background Hematologic and biochemical reference intervals (RIs) provide valuable data
for the nutritional status and clinical diagnosis of animals. However, the specific hematologic …

C1-inhibitor: an anti-inflammatory reagent with therapeutic potential

M Kirschfink, TE Mollnes - Expert Opinion on Pharmacotherapy, 2001 - Taylor & Francis
Excessive activation of the protein cascade systems often leads to severe inflammatory
tissue destruction with potential life-threatening outcome. These include clinical disorders …

Analysis of the control of the anti-gal immune response in a non-human primate by galactose α1-3 galactose trisaccharide-polyethylene glycol conjugate

LE Diamond, GW Byrne, A Schwarz, TA Davis… - …, 2002 - journals.lww.com
Background. The current limitation to the clinical application of xenotransplantation using pig
organs is a rejection process that has been termed delayed xenograft rejection or acute …