Challenges of fluoride pollution in environment: mechanisms and pathological significance of toxicity–a review

S Wu, Y Wang, M Iqbal, K Mehmood, Y Li, Z Tang… - Environmental …, 2022 - Elsevier
Fluoride is an important trace element in the living body. A suitable amount of fluoride has a
beneficial effect on the body, but disproportionate fluoride entering the body will affect …

The pathogenesis of endemic fluorosis: Research progress in the last 5 years

W Wei, S Pang, D Sun - Journal of cellular and molecular …, 2019 - Wiley Online Library
Fluorine is one of the trace elements necessary for health. It has many physiological
functions, and participates in normal metabolism. However, fluorine has paradoxical effects …

Cellulose for sustainable triboelectric nanogenerators

J Zhou, H Wang, C Du, D Zhang, H Lin… - Advanced Energy …, 2022 - Wiley Online Library
Triboelectric nanogenerators (TENGs) are an emerging technology capable of converting
the ambient mechanical energy into electricity, promising for complete utilization of the …

Hesperidin protects liver and kidney against sodium fluoride-induced toxicity through anti-apoptotic and anti-autophagic mechanisms

C Caglayan, FM Kandemir, E Darendelioğlu… - Life Sciences, 2021 - Elsevier
Aim High dose of fluoride intake is associated with toxic effects on liver and kidney tissues.
One approach to tackle these toxicities is using natural antioxidants as supplements. This …

[HTML][HTML] Sodium fluoride causes oxidative stress and apoptosis in the mouse liver

Y Lu, Q Luo, H Cui, H Deng, P Kuang, H Liu… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
The current study was conducted to investigate the effect of sodium fluoride (NaF) on the
oxidative stress and apoptosis as well as their relationship in the mouse liver by using …

Protective effects of pomegranate (Punica granatum) and its main components against natural and chemical toxic agents: A comprehensive review

A Hosseini, BM Razavi, H Hosseinzadeh - Phytomedicine, 2023 - Elsevier
Background Different chemical toxicants or natural toxins can damage human health
through various routes such as air, water, fruits, foods, and vegetables. Purpose Herbal …

Melatonin-mediated upregulation of Sirt3 attenuates sodium fluoride-induced hepatotoxicity by activating the MT1-PI3K/AKT-PGC-1α signaling pathway

C Song, J Zhao, B Fu, D Li, T Mao, W Peng… - Free Radical Biology …, 2017 - Elsevier
Mitochondrial reactive oxygen species (ROS) production has been implicated in the
pathogenesis of fluoride toxicity in liver. Melatonin, an indolamine synthesized in the pineal …

Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes

Y Zhao, Y Li, J Wang, RK Manthari, J Wang - Archives of toxicology, 2018 - Springer
Previous studies have reported that excessive fluoride exposure induced liver damage.
However, the underlying mechanism of fluoride-induced hepatic toxicity is still unclear …

Recent advances in cellular effects of fluoride: an update on its signalling pathway and targeted therapeutic approaches

AH Nagendra, B Bose, S Shenoy P - Molecular Biology Reports, 2021 - Springer
Fluoride is a natural element essential in minute quantities in human's to maintain dental
and skeletal health. However, the disease fluorosis manifests itself due to excessive fluoride …

Estrogen deficiency aggravates fluoride-induced liver damage and lipid metabolism disorder in rats

Y Yu, B Zhou, Y Yang, CX Guo, J Zhao… - Biological Trace Element …, 2022 - Springer
Estrogen exerts essential role in liver metabolism, and its deficiency is frequently
accompanied by a series of metabolic disorder diseases. To investigate the role of estrogen …