T‐cell activation–induced marker assays in health and disease

C Poloni, C Schonhofer, S Ivison… - … and Cell Biology, 2023 - Wiley Online Library
Activation‐induced marker (AIM) assays have proven to be an accessible and rapid means
of antigen‐specific T‐cell detection. The method typically involves short‐term incubation of …

Vaccines and monoclonal antibodies: new tools for malaria control

K Miura, Y Flores-Garcia, CA Long… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

[HTML][HTML] Structural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design

N Shukla, WK Tang, NH Tolia - Scientific Reports, 2022 - nature.com
Pfs28 is a Plasmodium falciparum malaria transmission-blocking vaccine candidate that is
anchored to the parasite surface through a C-terminal glycosylphosphatidylinositol (GPI) …

[PDF][PDF] 疟疾传播阻断疫苗的研究进展

王姗姗, 赵龙玉, 全芯, 薛庆节, 谭文彬, 李士根… - 中国病原生物学杂志, 2022 - cjpb.org
疟疾是经按蚊叮咬或输入带疟原虫者的血液而感染疟原虫所引起的虫媒传染病.
蚊虫易被疟原虫感染并传播病原体是消除疟疾面临的一个巨大挑战. 疟疾传播阻断疫苗旨在阻断 …

[HTML][HTML] Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study

M Iyori, AM Blagborough, T Mizuno, Y Abe… - Frontiers in …, 2022 - frontiersin.org
The Malaria Vaccine Technology Roadmap 2013 (World Health Organization) aims to
develop safe and effective vaccines by 2030 that will offer at least 75% protective efficacy …

[HTML][HTML] How to Accelerate Early Stage of Malaria Vaccine Development by Optimizing Functional Assays

K Miura - Vaccines, 2024 - mdpi.com
While two Plasmodium falciparum circumsporozoite protein-based pre-erythrocytic vaccines
(PEV), RTS, S and R21, have been approved by the WHO, no blood-stage vaccine (BSV) or …

Efforts to Develop Pfs25 Vaccines.

DC Kaslow - The American Journal of Tropical Medicine and …, 2022 - europepmc.org
Acknowledging the fallibilities of recalling events from more than three decades ago, the
recollection of Richard Carter's impact on the identification and development of Pfs25, a …

[HTML][HTML] Malaria & mRNA Vaccines: A Possible Salvation from One of the Most Relevant Infectious Diseases of the Global South

Y Borkens - Acta Parasitologica, 2023 - Springer
Malaria is one of the most dangerous infectious diseases in the world. It occurs in tropical
and subtropical regions and affects about 40% of the world´ s population. In endemic …

[HTML][HTML] Malaria-Antigene in der Ära der mRNA-Impfstoffe

Y Borkens - Monatsschrift Kinderheilkunde, 2022 - Springer
Bereits in den frühen 1990er-Jahren wurde erstmals eine durch einen mRNA-Impfstoff
ausgelöste Immunantwort beschrieben. Seitdem wurden mRNA-Impfstoffe für eine mögliche …

[HTML][HTML] Malaria-Antigene in der Ära der mRNA-Impfstoffe: Mögliche Rettungen vor einer der relevantesten und gefährlichsten Kinderkrankheiten des Globalen …

Y Borkens - Monatsschrift Kinderheilkunde, 2022 - ncbi.nlm.nih.gov
Bereits in den frühen 1990er-Jahren wurde erstmals eine durch einen mRNA-Impfstoff
ausgelöste Immunantwort beschrieben. Seitdem wurden mRNA-Impfstoffe für eine mögliche …