Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders
The intestine harbours a complex array of microorganisms collectively known as the gut
microbiota. The past two decades have witnessed increasing interest in studying the gut …
microbiota. The past two decades have witnessed increasing interest in studying the gut …
Crohn's disease
G Roda, S Chien Ng, PG Kotze, M Argollo… - Nature Reviews …, 2020 - nature.com
Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …
Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysine
Microglial function declines during aging. The interaction of microglia with the gut microbiota
has been well characterized during development and adulthood but not in aging. Here, we …
has been well characterized during development and adulthood but not in aging. Here, we …
The microbiome and inflammatory bowel disease
KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
Inflammatory bowel disease (IBD) is a chronic immune-mediated disease affecting the
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …
gastrointestinal tract. IBD consists of 2 subtypes: ulcerative colitis and Crohn disease. IBD is …
Host–microbiota interactions in inflammatory bowel disease
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
Alteration of gut microbiota in inflammatory bowel disease (IBD): cause or consequence? IBD treatment targeting the gut microbiome
Inflammatory bowel disease (IBD) is a chronic complex inflammatory gut pathological
condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …
condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …
Microbial genes and pathways in inflammatory bowel disease
Perturbations in the intestinal microbiome are implicated in inflammatory bowel disease
(IBD). Studies of treatment-naive patients have identified microbial taxa associated with …
(IBD). Studies of treatment-naive patients have identified microbial taxa associated with …
'Green'nanotherapeutics from tea leaves for orally targeted prevention and alleviation of colon diseases
M Zu, D Xie, BSB Canup, N Chen, Y Wang, R Sun… - Biomaterials, 2021 - Elsevier
Although synthesized nanotherapeutics (NTs) are attractive for the oral treatment of colon
diseases, their clinical translations are constrained by the unsatisfactory therapeutic …
diseases, their clinical translations are constrained by the unsatisfactory therapeutic …
Targeting immune cell circuits and trafficking in inflammatory bowel disease
MF Neurath - Nature immunology, 2019 - nature.com
Inflammatory bowel diseases (IBDs) such as Crohn's disease and ulcerative colitis are
characterized by uncontrolled activation of intestinal immune cells in a genetically …
characterized by uncontrolled activation of intestinal immune cells in a genetically …
The gut microbiome and inflammatory bowel diseases
Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental
factors, and gut microbiota, where each is necessary but not sufficient to cause disease …
factors, and gut microbiota, where each is necessary but not sufficient to cause disease …