Recent advances on the molecular mechanisms of exercise-induced improvements of cognitive dysfunction

Y Lu, FQ Bu, F Wang, L Liu, S Zhang, G Wang… - Translational …, 2023 - Springer
Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

[HTML][HTML] The impact of aerobic and resistance training intensity on markers of neuroplasticity in health and disease

T Hortobágyi, T Vetrovsky, GM Balbim… - Ageing Research …, 2022 - Elsevier
Objective To determine the effects of low-vs. high-intensity aerobic and resistance training
on motor and cognitive function, brain activation, brain structure, and neurochemical …

Intensive exercise ameliorates motor and cognitive symptoms in experimental Parkinson's disease restoring striatal synaptic plasticity

G Marino, F Campanelli, G Natale, M De Carluccio… - Science …, 2023 - science.org
Intensive physical activity improves motor functions in patients with Parkinson's disease (PD)
at early stages. However, the mechanisms underlying the beneficial effects of exercise on …

Does exercise attenuate disease progression in people with Parkinson's disease? A systematic review with meta-analyses

JA Li, MB Loevaas, C Guan, L Goh… - … and Neural Repair, 2023 - journals.sagepub.com
Introduction Exercise has many benefits for people with Parkinson's disease (PD) and has
been suggested to modify PD progression, but robust evidence supporting this is lacking …

Type 2 diabetes and Parkinson's disease: a focused review of current concepts

PW Cullinane, E de Pablo Fernandez… - Movement …, 2023 - Wiley Online Library
Highly reproducible epidemiological evidence shows that type 2 diabetes (T2D) increases
the risk and rate of progression of Parkinson's disease (PD), and crucially, the repurposing …

Medical, surgical, and physical treatments for Parkinson's disease

T Foltynie, V Bruno, S Fox, AA Kühn, F Lindop, AJ Lees - The Lancet, 2024 - thelancet.com
Although dopamine replacement therapy remains a core component of Parkinson's disease
treatment, the onset of motor fluctuations and dyskinetic movements might require a range of …

[HTML][HTML] Exercise and gait/movement analyses in treatment and diagnosis of Parkinson's Disease

J Burtscher, EM Moraud, D Malatesta, GP Millet… - Ageing Research …, 2023 - Elsevier
Cardinal motor symptoms in Parkinson's disease (PD) include bradykinesia, rest tremor
and/or rigidity. This symptomatology can additionally encompass abnormal gait, balance …

Lifestyle interventions for the prevention of Parkinson disease: a recipe for action

JM Janssen Daalen, S Schootemeijer, E Richard… - Neurology, 2022 - AAN Enterprises
The prevalence of Parkinson disease (PD) is growing fast, amplifying the quest for disease-
modifying therapies in early disease phases where pathology is still limited. Lifestyle …

A comprehensive approach to Parkinson's disease: addressing its molecular, clinical, and therapeutic aspects

M Muleiro Alvarez, G Cano-Herrera… - International Journal of …, 2024 - mdpi.com
Parkinson's disease (PD) is a gradually worsening neurodegenerative disorder affecting the
nervous system, marked by a slow progression and varied symptoms. It is the second most …

Molecular mechanisms underlying the neuroprotection of environmental enrichment in Parkinson's disease

TA Alarcón, SM Presti-Silva, APT Simões… - Neural Regeneration …, 2023 - journals.lww.com
Parkinson's disease is the most common movement disorder, affecting about 1% of the
population over the age of 60 years. Parkinson's disease is characterized clinically by …