Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and
Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized …

Background As an anthracycline antibiotic, doxorubicin (DOX) is one of the most potent and
widely used chemotherapeutic agents for various types of solid tumors. Unfortunately …

Chemotherapy, radiotherapy, targeted therapy, and immunotherapy have brought hope to
cancer patients. With the prolongation of survival of cancer patients and increased clinical …

Paraquat (PQ) is a herbicide agent commonly used in agricultural applications.
Hepatotoxicity is among clinical complications associated with PQ intoxication. Oxidative …

Doxorubicin (DOX), a potent broad‑spectrum chemotherapeutic agent used for the treatment
of several types of cancer, is largely limited due to its serious side effects on non‑target …

Cardiomyocyte apoptosis is an important event in doxorubicin (DOX)-induced cardiac injury.
The aim of the present study was to investigate the protection of berberine (Ber) against …

Chemotherapy and radiotherapy are mainstay treatments for cancer patients. However, their
clinical outcomes are highly limited by the resistance of malignant tumors to these therapies …

Serum levels of cardiac troponins serve as biomarkers of myocardial injury. However,
troponins are released into the serum only after damage to cardiac tissue has occurred …

Doxorubicin, a very potent and often used anti-cancer drug, is largely limited due to the dose-
related toxic effects. The present study investigated whether berberine, a natural product …

Berberis vulgaris L (B. vulgaris) and its main constituent berberine have been used in
traditional medicine for a long time. This medicinal plant and berberine have many …