New progress in the pharmacology of protocatechuic acid: A compound ingested in daily foods and herbs frequently and heavily
J Song, Y He, C Luo, B Feng, F Ran, H Xu, Z Ci… - Pharmacological …, 2020 - Elsevier
Protocatechuic acid is a natural phenolic acid, which widely exists in our daily diet and
herbs. It is also one of the main metabolites of complex polyphenols, such as anthocyanins …
herbs. It is also one of the main metabolites of complex polyphenols, such as anthocyanins …
[HTML][HTML] Targeting apoptotic pathway of cancer cells with phytochemicals and plant-based nanomaterials
Apoptosis is the elimination of functionally non-essential, neoplastic, and infected cells via
the mitochondrial pathway or death receptor pathway. The process of apoptosis is highly …
the mitochondrial pathway or death receptor pathway. The process of apoptosis is highly …
[HTML][HTML] Cancer and apoptosis: The apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics
Cancer is a multifactorial, multi-stage disease, including complex cascades of signaling
pathways—the cell growth governed by dysregulated and abrupt cell division. Due to the …
pathways—the cell growth governed by dysregulated and abrupt cell division. Due to the …
[HTML][HTML] Erastin decreases radioresistance of NSCLC cells partially by inducing GPX4‑mediated ferroptosis
X Pan, Z Lin, D Jiang, Y Yu, D Yang… - Oncology …, 2019 - spandidos-publications.com
The aim of the present study was to examine whether erastin influences radioresistance in
non‑small cell lung cancer (NSCLC) cells and produce a preliminary investigation into its …
non‑small cell lung cancer (NSCLC) cells and produce a preliminary investigation into its …
Gallic acid and gallates in human health and disease: do mitochondria hold the key to success?
Gallic acid and gallate esters are widely used as dietary supplements or additives with
clinical significances. Over the last few decades, a large number of publications have been …
clinical significances. Over the last few decades, a large number of publications have been …
[HTML][HTML] Withaferin A induces ROS-mediated paraptosis in human breast cancer cell-lines MCF-7 and MDA-MB-231
K Ghosh, S De, S Das, S Mukherjee… - PLoS …, 2016 - journals.plos.org
Advancement in cancer therapy requires a better understanding of the detailed mechanisms
that induce death in cancer cells. Besides apoptosis, themode of other types of cell death …
that induce death in cancer cells. Besides apoptosis, themode of other types of cell death …
Cancer‐Associated Fibroblasts Hinder Lung Squamous Cell Carcinoma Oxidative Stress‐Induced Apoptosis via METTL3 Mediated m6A Methylation of COL10A1
Y Li, X Li, M Deng, C Ye, Y Peng… - Oxidative medicine and …, 2022 - Wiley Online Library
Background. Cancer‐associated fibroblasts (CAFs) within the tumor microenvironment are
key players in tumorigenesis and tumor development. Nevertheless, the regulatory …
key players in tumorigenesis and tumor development. Nevertheless, the regulatory …
An enhanced targeted identification strategy for the selective identification of flavonoid O-glycosides from Carthamus tinctorius by integrating offline two-dimensional …
C Yao, W Yang, W Si, Y Shen, N Zhang, H Chen… - … of Chromatography a, 2017 - Elsevier
Targeted identification of potentially bioactive molecules from herbal medicines is often
stymied by the insufficient chromatographic separation, ubiquitous matrix interference, and …
stymied by the insufficient chromatographic separation, ubiquitous matrix interference, and …
Gallic acid promotes ferroptosis in hepatocellular carcinoma via inactivating Wnt/β-catenin signaling pathway
J Xie, H Wang, W Xie, Y Liu, Y Chen - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
Hepatocellular carcinoma (HCC) has high morbidity and mortality, and effective therapies
are lacking. Gallic acid (GA), a natural phenolic compound derived from plants, has been …
are lacking. Gallic acid (GA), a natural phenolic compound derived from plants, has been …
DEPDC1, negatively regulated by miR-26b, facilitates cell proliferation via the up-regulation of FOXM1 expression in TNBC
L Zhang, Y Du, S Xu, Y Jiang, C Yuan, L Zhou, X Ma… - Cancer letters, 2019 - Elsevier
Triple negative breast cancer (TNBC), characterized by lack of estrogen receptors,
progesterone hormone receptors, and HER2 overexpression, is a more aggressive high …
progesterone hormone receptors, and HER2 overexpression, is a more aggressive high …