Retro-inverso analogs of spadin display increased antidepressant effects
G Gaudriault, C Heurteaux, J Mazella, M Borsotto… - 2021 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
Serum Sortilin-Derived Propeptide Concentrations as Markers of Long Time Post-Stroke Depression
E Mazella, AM Bordet, B Accart, M Borsotto… - Available at SSRN … - papers.ssrn.com
Background: Post-Stroke Depression (PSD) is a dramatic consequence of stroke that
considerably modifies the neurological recovery and the quality of life. To date, identification …
considerably modifies the neurological recovery and the quality of life. To date, identification …
Potential of Heterogeneous Compounds as Antidepressants: A Narrative Review
G Hu, M Zhang, Y Wang, M Yu, Y Zhou - International Journal of …, 2022 - mdpi.com
Depression is a globally widespread disorder caused by a complicated interplay of social,
psychological, and biological factors. Approximately 280 million people are suffering from …
psychological, and biological factors. Approximately 280 million people are suffering from …
[PDF][PDF] Research Article Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin
C Hivelin, S Béraud-Dufour, C Devader… - 2016 - academia.edu
Inhibition of the potassium channels TREK-1 by spadin (SPA) is currently thought to be a
promising therapeutic target for the treatment of depression. Since these channels are …
promising therapeutic target for the treatment of depression. Since these channels are …
Investigations into the structure, function and pharmacology of TREK K2P potassium channels
C McClenaghan - 2015 - ora.ox.ac.uk
TREK channels are polymodal potassium channels which act as integrators of diverse
chemical and physical stimuli to dynamically control the cellular membrane potential. How …
chemical and physical stimuli to dynamically control the cellular membrane potential. How …