Organelles perform critical biological functions due to their distinct molecular composition
and internal environment. Disorders in organelles or their interacting networks have been …

Mitochondria play a crucial part in the cell's ability to adapt to the changing
microenvironments and their dysfunction is associated with an extensive array of illnesses …

Although Type I photosensitizers with aggregation-induced emission (AIE) characteristics
have thrived as alternative tools for cancer photodynamic therapy (PDT) thanks to their …

The mitochondrial permeability transition (mPT) directly affects mitochondrial function in
macrophages. Under inflammatory conditions, mitochondrial calcium ion (mitoCa2+) …

Mitochondria-targeting damage has become a popular therapeutic option for tumor
metastasis; however, its efficacy is limited by the adaptive rescue capacity of nuclei. There is …

Introduction Cancer of the bladder is one of the most common and life-threatening.
Compared with traditional delivery methods, intravesical administration reduces the amount …

Amalgamation of the reactive oxygen species (ROS)-responsive stimulus with nanoparticles
has gained considerable interest owing to their high tumor specificity. Hypoxia plays a …

Dendritic cells (DCs) play central role in adaptive antitumor immunity, while their function is
often hampered by low immunogenicity of tumor tissues and surrounding hostile …

The tumor microenvironment affects the structure and metabolic function of mitochondria in
tumor cells. This process involves changes in metabolic activity, an increase in the amount …

Cancer cells reprogram their metabolism to meet the growing demand of bioenergy and
biosynthesis. The metabolic profile of cancer cells usually includes dysregulation of main …