NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings

O An, GM Dall'Olio, TP Mourikis… - Nucleic acids …, 2016 - academic.oup.com
Abstract The Network of Cancer Genes (NCG, http://ncg. kcl. ac. uk/) is a manually curated
repository of cancer genes derived from the scientific literature. Due to the increasing …

Identification of infectious disease-associated host genes using machine learning techniques

RK Barman, A Mukhopadhyay, U Maulik, S Das - BMC bioinformatics, 2019 - Springer
Background With the global spread of multidrug resistance in pathogenic microbes,
infectious diseases emerge as a key public health concern of the recent time. Identification …

Integrating network, sequence and functional features using machine learning approaches towards identification of novel Alzheimer genes

S Jamal, S Goyal, A Shanker, A Grover - BMC genomics, 2016 - Springer
Background Alzheimer's disease (AD) is a complex progressive neurodegenerative disorder
commonly characterized by short term memory loss. Presently no effective therapeutic …

Mutations in the IRBIT domain of ITPR1 are a frequent cause of autosomal dominant nonprogressive congenital ataxia

S Barresi, M Niceta, P Alfieri, V Brankovic… - Clinical …, 2017 - Wiley Online Library
Congenital ataxias are nonprogressive neurological disorders characterized by neonatal
hypotonia, developmental delay and ataxia, variably associated with intellectual disability …

Protein–protein interaction network with machine learning models and multiomics data reveal potential neurodegenerative disease-related proteins

X Yu, S Lai, H Chen, M Chen - Human Molecular Genetics, 2020 - academic.oup.com
Research of protein–protein interaction in several model organisms is accumulating since
the development of high-throughput experimental technologies and computational methods …

AlzGenPred: A CatBoost based method using network features to classify the Alzheimers Disease associated genes from the high throughput sequencing data

R Shukla, TR Singh - bioRxiv, 2023 - biorxiv.org
Background and Objective: AD is a progressive neurodegenerative disorder characterized
by memory loss. Due to the advancement in next-generation sequencing technologies, an …

Identification of Novel Inhibitors and Biomarkers for Alzheimer's Disease using Computational Systems Polypharmacology and Machine Learning Approach

R Shukla, TR Singh - 2022 - ir.juit.ac.in
The current research is focused on the management of the pathophysiology of the
Alzheimer's Disease (AD). The AD is a neurological irreversible disease characterized by …

Annotation of Five Genes in the DNA Mismatch Repair Pathway of Kytococcus Sedentarius

JM Gawron - 2014 - dspace.sunyconnect.suny.edu
Abstract Annotation of Five Genes in DNA Mismatch Repair Pathway of Kytococcus
Sedentarius Joseph M. Gawron, Rama Dey-Rao, Ph. D., Stephen T. Koury, Ph. D …

[引用][C] 基于多特征融合的基因调控网络构建方法研究

孟军, 周广博, 黄楚冰 - 小型微型计算机系统, 2016