CRISPR‐Cas biochemistry and CRISPR‐based molecular diagnostics

Z Weng, Z You, J Yang, N Mohammad… - Angewandte Chemie …, 2023 - Wiley Online Library
Polymerase chain reaction (PCR)‐based nucleic acid testing has played a critical role in
disease diagnostics, pathogen surveillance, and many more. However, this method requires …

Recent advancements in nanomaterials-based aptasensors for the detection of emerging contaminants in foodstuffs

L Hejji, A Azzouz, D Kukkar, KH Kim - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The presence of emerging contaminants (ECs) can pose human health risks in diverse
forms such as endocrine disruption, tumors, reproductive failure, and fetal damage. It is thus …

Extracellular vesicles: techniques and biomedical applications related to single vesicle analysis

J Zhang, J Wu, G Wang, L He, Z Zheng, M Wu… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) are extensively dispersed lipid bilayer membrane vesicles
involved in the delivery and transportation of molecular payloads to certain cell types to …

Theranostic signature of tumor-derived exosomes in cancer

S Kumar, R Dhar, LBSS Kumar, GG Shivji, R Jayaraj… - Medical Oncology, 2023 - Springer
Cancer is the most challenging global health crisis. In the recent times, studies on
extracellular vesicles (EVs) are adding a new chapter to cancer research and reports on EVs …

Towards artificial intelligence-enabled extracellular vesicle precision drug delivery

ZF Greenberg, KS Graim, M He - Advanced Drug Delivery Reviews, 2023 - Elsevier
Abstract Extracellular Vesicles (EVs), particularly exosomes, recently exploded into
nanomedicine as an emerging drug delivery approach due to their superior biocompatibility …

Single-cell analysis and classification according to multiplexed proteins via microdroplet-based self-driven magnetic surface-enhanced raman spectroscopy platforms …

J Wang, L Cong, W Shi, W Xu, S Xu - Analytical Chemistry, 2023 - ACS Publications
A microdroplet-based surface-enhanced Raman spectroscopy (microdroplet SERS) platform
was constructed to envelop individual cells in microdroplets, followed by the SERS detection …

Clinical impact of exosomes in colorectal cancer metastasis

S Ghosh, R Dhar, G Gurudas Shivji, D Dey… - ACS Applied Bio …, 2023 - ACS Publications
Cancer is a complex deadly disease that has caused a global health crisis in recent epochs.
Colorectal cancer (CRC) is the third most common malignant gastrointestinal disease. It has …

Plant-derived exosomes: a green approach for cancer drug delivery

S Madhan, R Dhar, A Devi - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Plant-derived exosomes (PDEs) are natural extracellular vesicles (EVs). In the current
decade, they have been highlighted for cancer therapeutic development. Cancer is a global …

Unlocking exosome-based theragnostic signatures: deciphering secrets of ovarian cancer metastasis

S Mukherjee, S Nag, N Mukerjee, S Maitra… - ACS …, 2023 - ACS Publications
Ovarian cancer (OC) is a common gynecological cancer worldwide. Unfortunately, the lack
of early detection methods translates into a substantial cohort of women grappling with the …

Exosome and epithelial–mesenchymal transition: A complex secret of cancer progression

R Dhar, A Devi, S Gorai, SK Jha… - Journal of cellular …, 2023 - Wiley Online Library
This short communication will enlighten the readers about the exosome and the epithelial‐
mesenchymal transition (EMT) related to several complicated events. It also highlighted the …