[HTML][HTML] Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics

BC Carlyle, SE Kandigian, J Kreuzer, S Das… - Neurobiology of …, 2021 - Elsevier
Alzheimer's disease (AD) is defined by the presence of abundant amyloid-β (Aβ) and tau
neuropathology. While this neuropathology is necessary for AD diagnosis, it is not sufficient …

Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease

N Jin, H Zhu, X Liang, W Huang, Q Xie, P Xiao… - Experimental …, 2017 - Elsevier
Accumulating evidences show that selenium dietary intake is inversely associated with the
mortality of Alzheimer's disease (AD). Sodium selenate has been reported to reduce …

How Wnt signaling builds the brain: bridging development and disease

R Noelanders, K Vleminckx - The Neuroscientist, 2017 - journals.sagepub.com
Wnt/β-catenin signaling plays a crucial role throughout all stages of brain development and
remains important in the adult brain. Accordingly, many neurological disorders have been …

Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20‐APP transgenic and wild‐type mice

C Tapia‐Rojas, NC Inestrosa - Journal of neurochemistry, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative pathology characterized by aggregates of
amyloid‐β (Aβ) and phosphorylated tau protein, synaptic dysfunction, and spatial memory …

Secretome of mesenchymal stem cells and its potential protective effects on brain pathologies

E Baez-Jurado, O Hidalgo-Lanussa… - Molecular …, 2019 - Springer
Previous studies have indicated that mesenchymal stem cells (MSCs) have a fundamental
role in the repair and regeneration of damaged tissues. There is strong evidence showing …

[HTML][HTML] Palmitoylethanolamide (PEA) as a potential therapeutic agent in Alzheimer's disease

S Beggiato, MC Tomasini, L Ferraro - Frontiers in pharmacology, 2019 - frontiersin.org
N-Palmitoylethanolamide (PEA) is a non-endocannabinoid lipid mediator belonging to the
class of the N-acylethanolamine phospolipids and was firstly isolated from soy lecithin, egg …

Current progress on neuroprotection induced by Artemisia, Ginseng, Astragalus, and Ginkgo traditional Chinese medicines for the therapy of Alzheimer's disease

Q Li, L Rubin, M Silva, S Li, C Yang… - Oxidative Medicine …, 2022 - Wiley Online Library
Aging is associated with the occurrence of diverse degenerative changes in various tissues
and organs and with an increased incidence of neurological disorders, especially …

[HTML][HTML] Differentially expressed genes in the brain of aging mice with cognitive alteration and depression-and anxiety-like behaviors

M Li, S Su, W Cai, J Cao, X Miao, W Zang… - Frontiers in Cell and …, 2020 - frontiersin.org
Despite the great increase in human lifespan with improved medical care, the physiological
and pathological changes such as memory and cognitive disorders and associated anxiety …

Signaling Mechanisms of Selective PPARγ Modulators in Alzheimer's Disease

M Govindarajulu, PD Pinky, J Bloemer… - PPAR …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by
abnormal protein accumulation, synaptic dysfunction, and cognitive impairment. The …

[HTML][HTML] Harnessing the stem cell niche in regenerative medicine: innovative avenue to combat neurodegenerative diseases

G Velikic, DM Maric, DL Maric, G Supic… - International journal of …, 2024 - mdpi.com
Regenerative medicine harnesses the body's innate capacity for self-repair to restore
malfunctioning tissues and organs. Stem cell therapies represent a key regenerative …