Updates on germline predisposition in pediatric hematologic malignancies: What is the role of flow cytometry?
N Demko, JT Geyer - Cytometry Part B: Clinical Cytometry, 2024 - Wiley Online Library
Hematologic neoplasms with germline predisposition have been increasingly recognized as
a distinct category of tumors over the last few years. As such, this category was added to the …
a distinct category of tumors over the last few years. As such, this category was added to the …
Advances in acute myeloid leukemia classification, prognostication and monitoring by flow cytometry
F Lucas, CB Hergott - Clinics in Laboratory Medicine, 2023 - labmed.theclinics.com
The categorization of acute myeloid leukemia (AML) into subsets with specific biological
characteristics and clinical outcomes is guided by morphologic, cytogenetic, and molecular …
characteristics and clinical outcomes is guided by morphologic, cytogenetic, and molecular …
Immunophenotype distinctions of CEBPA mutation subtypes in acute myeloid leukemia
Q Liu, L Qi, M Yang, X Zhang, F Li… - … Journal of Laboratory …, 2023 - Wiley Online Library
Introduction Acute myeloid leukemia (AML) patients with CEBPA double mutation (CEBPA
dm) were associated with distinct immunophenotypes and prognosis. Recently, both …
dm) were associated with distinct immunophenotypes and prognosis. Recently, both …
Diagnostic Workup of Acute Myeloid Leukemia: What Is Really Necessary? An Italian Survey
MT Voso, F Ferrara, S Galimberti, A Rambaldi… - Frontiers in …, 2022 - frontiersin.org
Acute myeloid leukemia (AML) is a heterogeneous disease with a wide variety of clinical
presentations, morphological features, and immunophenotypes. The diagnostic approaches …
presentations, morphological features, and immunophenotypes. The diagnostic approaches …
Laboratory evaluation and prognostication among adults and children with CEBPA‐mutant acute myeloid leukemia
H Mendoza, NA Podoltsev… - International journal of …, 2021 - Wiley Online Library
CEBPA‐mutant acute myeloid leukemia (AML) encompasses clinically and biologically
distinct subtypes of AML in both adults and children. CEBPA‐mutant AML may occur with …
distinct subtypes of AML in both adults and children. CEBPA‐mutant AML may occur with …
Digital PCR-based GRHL2 methylation testing in acute myeloid leukemia: diagnosis, prognosis and monitoring
J Hua, M Chu, C Wang, H Zhang, J Luan, Y Zhang… - …, 2024 - Taylor & Francis
Background: Acute myeloid leukemia (AML) is a challenging disease with high rates of
recurrence. The role of the cancer-related gene GRHL2 in AML has not been widely studied …
recurrence. The role of the cancer-related gene GRHL2 in AML has not been widely studied …
Droplet digital PCR for genetic mutations monitoring predicts relapse risk in pediatric acute myeloid leukemia
X Chen, L Liu, A Zhang, M Yi, Y Lan, Z Zheng… - International Journal of …, 2022 - Springer
Multiparameter flow cytometry (MFC)-based minimal residual disease has been a poor
predictor of prognosis in children with acute myeloid leukemia (AML). This study aimed to …
predictor of prognosis in children with acute myeloid leukemia (AML). This study aimed to …
Mutations in the bZip region of the CEBPA gene: A novel prognostic factor in patients with acute myeloid leukemia
JC Rivera, D Nuñez, E Millar, K Ramirez… - International Journal …, 2023 - Wiley Online Library
Background Hematopoiesis, the process of blood cell formation involves on a complex
network of transcription factors. Among them, the CCAAT‐enhancer‐binding protein alpha …
network of transcription factors. Among them, the CCAAT‐enhancer‐binding protein alpha …