Horizontal gene exchange in environmental microbiota

RI Aminov - Frontiers in microbiology, 2011 - frontiersin.org
Horizontal gene transfer (HGT) plays an important role in the evolution of life on the Earth.
This view is supported by numerous occasions of HGT that are recorded in the genomes of …

Neisseria gonorrhoeae vaccines: a contemporary overview

E Williams, KL Seib, CK Fairley… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Neisseria gonorrhoeae infection is an important public health issue, with an annual global
incidence of 87 million. N. gonorrhoeae infection causes significant morbidity and can have …

Nitric oxide regulation of bacterial biofilms

DP Arora, S Hossain, Y Xu, EM Boon - Biochemistry, 2015 - ACS Publications
Biofilms are surface-associated, multicellular communities of bacteria. Once established,
they are extremely difficult to eradicate by antimicrobial treatment. It has been demonstrated …

[HTML][HTML] Bacterial peroxidases–Multivalent enzymes that enable the use of hydrogen peroxide for microaerobic and anaerobic proliferation

DS Barreiro, RNS Oliveira, SR Pauleta - Coordination Chemistry Reviews, 2023 - Elsevier
Bacterial peroxidases are responsible for the reduction of hydrogen peroxide to water.
Found in the periplasm of gram-negative bacteria, they are one of the defense mechanisms …

Is gonococcal disease preventable? The importance of understanding immunity and pathogenesis in vaccine development

JL Edwards, MP Jennings, MA Apicella… - Critical reviews in …, 2016 - Taylor & Francis
Gonorrhea is a major, global public health problem for which there is no vaccine. The
continuing emergence of antibiotic-resistant strains raises concerns that untreatable …

Optimization of nitric oxide donors for investigating biofilm dispersal response in Pseudomonas aeruginosa clinical isolates

Y Cai, JS Webb - Applied microbiology and biotechnology, 2020 - Springer
Pseudomonas aeruginosa biofilms contribute heavily to chronic lung infection in cystic
fibrosis patients, leading to morbidity and mortality. Nitric oxide (NO) has been shown to …

Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease

N Castiglione, S Rinaldo, G Giardina… - Antioxidants & redox …, 2012 - liebertpub.com
Nitrite, previously considered physiologically irrelevant and a simple end product of
endogenous nitric oxide (NO) metabolism, is now envisaged as a reservoir of NO to be …

Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases

Y Nishida, S Yanagisawa, R Morita… - nature …, 2022 - nature.com
Antimicrobial resistance (AMR) is a global health problem. Despite the enormous efforts
made in the last decade, threats from some species, including drug-resistant Neisseria …

The Neisseria gonorrhoeae Biofilm Matrix Contains DNA, and an Endogenous Nuclease Controls Its Incorporation

CT Steichen, C Cho, JQ Shao… - Infection and …, 2011 - Am Soc Microbiol
Neisseria gonorrhoeae has been shown to produce biofilms both in experimental flow
chambers and in the human host. Our laboratory has shown that extracellular DNA is an …

The role of denitrification genes in anaerobic growth and virulence of Flavobacterium columnare

H Abdelhamed, SW Nho, A Karsi… - Journal of applied …, 2021 - academic.oup.com
Aims Comparative genomics analyses indicated that the Flavobacterium columnare genome
has unique denitrification genes relative to Flavobacterium psychrophilum and …