Tire-rubber related pollutant 6-PPD quinone: A review of its transformation, environmental distribution, bioavailability, and toxicity
X Hua, D Wang - Journal of Hazardous Materials, 2023 - Elsevier
The antioxidant 6-PPD has been widely used to prevent cracking and thermal oxidative
degradation and to extend the service life of tire rubber. 6-PPD quinone (6-PPDQ) is formed …
degradation and to extend the service life of tire rubber. 6-PPD quinone (6-PPDQ) is formed …
A mini review on 6PPD quinone: A new threat to aquaculture and fisheries
Numerous toxic substances are directly and indirectly discharged by humans into water
bodies, causing distress to the organisms living on it. 6PPD, an amino antioxidant from tires …
bodies, causing distress to the organisms living on it. 6PPD, an amino antioxidant from tires …
Widespread occurrence of two typical N, N'-substituted p-phenylenediamines and their quinones in humans: Association with oxidative stress and liver damage
S Song, Y Gao, S Feng, Z Cheng, H Huang… - Journal of Hazardous …, 2024 - Elsevier
While N, N'-substituted p-phenylenediamines (PPDs) and their quinone derivatives (PPDQs)
have been widely detected in the environment, there is currently limited data on their …
have been widely detected in the environment, there is currently limited data on their …
Exposure to 6-PPD quinone causes ferroptosis activation associated with induction of reproductive toxicity in Caenorhabditis elegans
Z Liu, Q Bian, D Wang - Journal of Hazardous Materials, 2024 - Elsevier
Abstract Exposure to N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6-
PPDQ) caused toxicity on Caenorhabditis elegans, including reproductive toxicity. However …
PPDQ) caused toxicity on Caenorhabditis elegans, including reproductive toxicity. However …
Exposure to 6-PPD Quinone at Environmentally Relevant Concentrations Inhibits Both Lifespan and Healthspan in C. elegans
X Hua, D Wang - Environmental Science & Technology, 2023 - ACS Publications
N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6-PPD), one of the most common
additives used in rubber, enters the environment due to significant emissions of tire wear …
additives used in rubber, enters the environment due to significant emissions of tire wear …
Comparison of intestinal toxicity in enhancing intestinal permeability and in causing ROS production of six PPD quinones in Caenorhabditis elegans
Y Wang, G Liang, J Chao, D Wang - Science of the Total Environment, 2024 - Elsevier
As the derivatives of p-phenylenediamines (PPDs), PPD quinones (PPDQs) have received
increasing attention due to their possible exposure risk. We compared the intestinal toxicity …
increasing attention due to their possible exposure risk. We compared the intestinal toxicity …
Environmentally realistic dose of tire-derived metabolite 6PPD-Q exposure causes intestinal jejunum and ileum damage in mice via cannabinoid receptor-activated …
Y Yang, N Sun, J Lv, H Chen, H Wang, J Xu… - Science of The Total …, 2024 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPD-Q) is a
quinone derivative of a common tire additive 6PPD, whose occurrence has been widely …
quinone derivative of a common tire additive 6PPD, whose occurrence has been widely …
Exposure to 6-PPD quinone causes damage on mitochondrial complex I/II associated with lifespan reduction in Caenorhabditis elegans
X Hua, G Liang, J Chao, D Wang - Journal of Hazardous Materials, 2024 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6-PPDQ) is an
emerging pollutant transformed from 6-PPD. However, the effect of 6-PPDQ exposure on …
emerging pollutant transformed from 6-PPD. However, the effect of 6-PPDQ exposure on …
Disruption of dopamine metabolism by exposure to 6-PPD quinone in Caenorhabditis elegans
X Hua, D Wang - Environmental Pollution, 2023 - Elsevier
Caenorhabditis elegans is a useful model for examining metabolic processes and related
mechanisms. We here examined the effect of exposure to N-(1, 3-dimethylbutyl)-N′-phenyl …
mechanisms. We here examined the effect of exposure to N-(1, 3-dimethylbutyl)-N′-phenyl …
Chronic exposure to tire rubber-derived contaminant 6PPD-quinone impairs sperm quality and induces the damage of reproductive capacity in male mice
K Yao, Q Kang, W Liu, D Chen, L Wang, S Li - Journal of Hazardous …, 2024 - Elsevier
It has been reported that N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone
(6PPD-Q), a derivative of the tire antioxidant, N-(1, 3-dimethylbutyl)-N′-phenyl-p …
(6PPD-Q), a derivative of the tire antioxidant, N-(1, 3-dimethylbutyl)-N′-phenyl-p …