Nanoparticles overcome adaptive immune resistance and enhance immunotherapy via targeting tumor microenvironment in lung cancer

X Zhang, X Wang, L Hou, Z Xu, Y Liu… - Frontiers in …, 2023 - frontiersin.org
Lung cancer is one of the common malignant cancers worldwide. Immune checkpoint
inhibitor (ICI) therapy has improved survival of lung cancer patients. However, ICI therapy …

Tumor microenvironment as a therapeutic target in melanoma treatment

N Kharouf, TW Flanagan, SY Hassan, H Shalaby… - Cancers, 2023 - mdpi.com
Simple Summary As a solid tumor, melanoma is not only a tumor mass of monolithic tumor
cells, but it also contains supporting stroma, extracellular matrix (ECM), and soluble …

Desorption Separation Ionization Mass Spectrometry (DSI-MS) for Rapid Analysis of COVID-19

Y Wang, W Ma, Y Qu, K Jia, J Liu, Y Li, L Jiang… - Analytical …, 2024 - ACS Publications
During the coronavirus disease 2019 (COVID-19) pandemic, which has witnessed over 772
million confirmed cases and over 6 million deaths globally, the outbreak of COVID-19 has …

Bibliometric analysis of rheumatic immune related adverse events associated with immune checkpoint inhibitors

L Zeng, G Ma, K Chen, Q Zhou - Frontiers in Immunology, 2023 - frontiersin.org
Background Immune checkpoint inhibitors (ICIs) has emerged as a popular cancer treatment
approach. However, non-specific activation of T cells by ICIs can lead to immune-related …

[HTML][HTML] Efficacy and safety assessment of intrathoracic perfusion chemotherapy combined with immunological factor interleukin-2 in the treatment of advanced non …

Q Cao, J Zhu, X Wu, J Li, Y Chen, Y You, X Li… - Journal of …, 2024 - ncbi.nlm.nih.gov
Objective: This study evaluated the efficacy and safety of the gemcitabine and oxaliplatin
intrathoracic perfusion chemotherapy (IPCGOR) regimen combined with interleukin-2 (IL-2) …

Exploring the clinical significance of IL-38 correlation with PD-1, CTLA-4, and FOXP3 in colorectal cancer draining lymph nodes

L Yuan, Z Tan, J Huang, F Chen, BD Hambly… - Frontiers in …, 2024 - frontiersin.org
Introduction Colorectal cancer (CRC) presents a substantial challenge characterized by
unacceptably high mortality and morbidity, primarily attributed to delayed diagnosis and …

[HTML][HTML] The role of circular RNAs in regulating resistance to cancer immunotherapy: mechanisms and implications

Y Ma, T Wang, X Zhang, P Wang, F Long - Cell Death & Disease, 2024 - nature.com
Cancer immunotherapy has rapidly transformed cancer treatment, yet resistance remains a
significant hurdle, limiting its efficacy in many patients. Circular RNAs (circRNAs), a novel …

Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment

Q Yin, SY Song, Y Bian, Y Wang, A Deng, J Lv… - Frontiers in …, 2024 - frontiersin.org
Background The interaction between pyroptosis—a form of programmed cell death—and
tumor immunity represents a burgeoning field of interest. Pyroptosis exhibits a dual role in …

Efficacy and safety of immune checkpoint inhibitors in hematologic malignancies

MT Bilgihan, AN Eryigit, R Ciftciler - Clinical Lymphoma Myeloma and …, 2023 - Elsevier
The emergence of immune checkpoint inhibitors (ICIs) has led to a dramatic paradigm shift
within the landscape of cancer treatment, igniting significant interest in their potential …

[PDF][PDF] Research progress of immune checkpoint LAG-3 in gastric cancer: a narrative review.

Y Guo, HZ Chu, JG Xu - European Review for Medical & …, 2023 - europeanreview.org
In recent years, the immunotherapy of gastric cancer has made a breakthrough. With the
emergence of immune checkpoint inhibitors, blocking the inhibitory molecules in the body …