Nucleic acids carry the building plans of living systems. As such, they can be exploited to
make cells produce a desired protein, or to shut down the expression of endogenous genes …

Fluorescent protein technology has evolved to include genetically encoded biosensors that
can monitor levels of ions, metabolites, and enzyme activities as well as protein …

This review briefly discusses the main approaches for monitoring chloride (Cl−), the most
abundant physiological anion. Noninvasive monitoring of intracellular Cl−([Cl−] i) is a …

J. Neurochem.(2011) 116, 734–741. Abstract The Cys‐loop receptor family consists of
nicotinic acetylcholine receptors (nAChR), glycine receptor, GABA‐A and some other …

Chloride (Cl) participates in a variety of physiological functions. To study processes
connected with Cl homeostasis we need effective and quantitative probes allowing …

Monitoring of the intracellular concentrations of Cl− and H+ requires sensitive probes that
allow reliable quantitative measurements without perturbation of cell functioning. For these …

Key points• The mouse retina has become a key model for research on the function and
dysfunction of the early stages of vision, but its photoreceptors have proven difficult to …

Chloride is the most abundant physiological anion and participates in a variety of cellular
processes including trans-epithelial transport, cell volume regulation, and regulation of …

Fluorescence microscopy with membrane-permeable ion-sensitive fluorophores allows the
non-invasive determination of intracellular ion concentrations. Chloride is the major anion of …

This protocol describes a technique for high-resolution chloride imaging of living cells using
a quinoline-based chloride (Cl−) indicator dye, MQAE (N-[6-methoxyquinolyl] acetoethyl …