The effect of the inaccuracy of the input function on CBF measured by the H152O
autoradiographic method was investigated. In H152O autoradiography the measured input …

A system for CBF measurement using an H215O autoradiographic method and positron
emission tomography (PET) has been designed and installed as a clinical tool. Following an …

An unbiased algorithm of generalized linear least squares (GLLS) for parameter estimation
of nonuniformly sampled biomedical systems is proposed. The basic theory and detailed …

To investigate local metabolic and hemodynamic interrelationships during functional
activation of the brain, paired studies of local cerebral glucose utilization (lCMRGlc) and …

Regional cerebral blood flow (rCBF) and regional cerebral metabolic rate of glucose
(rCMRglc) were measured in aged and young monkeys by positron emission tomography …

In order to investigate the validity of the single compartment model in measuring CBF with
the use of 15O-labeled water (H215O), dynamic positron emission tomography (PET) was …

With the advent of positron emission tomography (PET), a variety of techniques have been
developed to measure local cerebral blood flow (LCBF) noninvasively in humans. A …

Two common assumptions made in most positron emission tomography (PET) cerebral
blood flow techniques have been examined in detail. These are (1) that the blood-borne …

To further our understanding of the best way to measure regional CBF with positron
emission tomography (PET), we directly compared two candidate tracers ([15O] water and …

FG7142 is a benzodiazepine partial inverse agonist, which is known as a pharmacological
stressor. Several reports demonstrated that FG7142 produced anxiety in humans, non …