Nutrient-response curves are nonlinear and, as is true of other curves that define the rates of
biological reactions, these curves can be described by rational polynomials. These nutrient …

Five separate methods, paper chromatography, ethanol solubility, pH dependence,
enzymatic activity, and NMR saturation transfer, were used to study the coupling of pyruvate …

Mathematical models are useful for analyzing metabolic problems. To build up these
models, we need:(1) A scheme of the target system,(2) Measurements of concentrations and …

Modeling a hormone system requires a number of simplifying assumptions. Often, the final
conceptual model incorporates a number of aggregated processes that have no …

A computer program is described that derives the Flux and Concentration Control
Coefficients for linear and branched metabolic pathways. The program prompts the user to …

A program to simulate metabolic pathways on the basis of either kinetic data or data on the
steady state levels and fluxes using Biochemical Systems Theory is presented. Having …

During the past two decades, three new theories have been developed for the
representation and analysis of biochemical phenomena: Biochemical Systems Theory …

We study piecewise synergetic systems originating from Biochemical Systems Theory. In the
first part of the paper, the emphasis is put on practical calculations with such systems. We …

In the modeling of complex biological systems, and especially in the framework of the
description of metabolic pathways, the use of power-law models (such as S-systems and …

In this article we present a new methodology—Biochemical Systems Theory and Analysis—
as an alternative to traditional parametric statistical procedures for investigating differences …