Coined three decades ago, the term aptamer and directed evolution have now reached their
maturity. The concept that nucleic acid could modulate the activity of target protein as ligand …

Xeno nucleic acids (XNA) are an increasingly important class of hypermodified nucleic acids
with great potential in bioorganic chemistry and synthetic biology. Glycol nucleic acid (GNA) …

Ferrocenylated glycol nucleic acid (Fc-GNA) components are rarely studied in the field of
xeno nucleic acid (XNA) chemistry. As an attempt to contribute to XNA chemistry, in the …

The knowledge pertaining to the chemistry and biological activity of glycol nucleic acid
(GNA) components, like nucleosides and nucleotides, is still very limited. Herein we report …

Recently, various AIE-based materials with new characteristics and functions have been
developing for different fields. Many chiral polymers are attracting the research interests for …

Background: Aptamers, consisting of single-stranded DNA or RNA, have secondary and
tertiary structures which could bind specifically to target molecules. They are characterized …

Organometallic compounds have gained popularity as potent anti-cancer therapeutic
prospects in recent years. The constant threat of drug-resistant cancer and the limited …

The copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction was used as a major
tool for the synthesis of the artificial 5ʹ-T-click (Fc)-T-clickʹ (Fc)-A-3ʹtrinucleotide and its …

In consideration of various advantages such as less harm, higher sensitivity, and deeper
imaging depth, etc., AIE materials with longwave emission are attracting extensive attention …

In this paper, we report the Yb (OTf) 3‐mediated etherification reaction that allowed
obtaining R, R and S, R isomers of ferrocenyl glycol nucleic acid (Fc‐GNA) nucleosides from …