[HTML][HTML] A review of artificial intelligence, big data, and blockchain technology applications in medicine and global health

VK Chattu - Big Data and Cognitive Computing, 2021 - mdpi.com
Artificial intelligence (AI) programs are applied to methods such as diagnostic procedures,
treatment protocol development, patient monitoring, drug development, personalized …

[HTML][HTML] Phosphorescent metal complexes as theranostic anticancer agents: combining imaging and therapy in a single molecule

CP Tan, YM Zhong, LN Ji, ZW Mao - Chemical Science, 2021 - pubs.rsc.org
Phosphorescent metal complexes are a new kind of multifunctional antitumor compounds
that can integrate imaging and antitumor functions in a single molecule. In this minireview …

Nanotechnology-based approaches overcome lung cancer drug resistance through diagnosis and treatment

J Li, L Zhu, HF Kwok - Drug Resistance Updates, 2023 - Elsevier
Lung cancer continues to be a malignant tumor with high mortality. Two obstacles interfere
with curative therapy of lung cancer:(i) poor diagnosis at the early stages, as symptoms are …

Applications of radiocomplexes with thiosemicarbazones and bis (thiosemicarbazones) in diagnostic and therapeutic nuclear medicine

GL Parrilha, RG dos Santos, H Beraldo - Coordination Chemistry Reviews, 2022 - Elsevier
Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Transforming nuclear medicine with nanoradiopharmaceuticals

I Roy, S Krishnan, AV Kabashin, IN Zavestovskaya… - ACS …, 2022 - ACS Publications
Nuclear medicine is expected to make major advances in cancer diagnosis and therapy;
tumor-targeted radiopharmaceuticals preferentially eradicate tumors while causing minimal …

[HTML][HTML] Radiopharmaceutical treatments for cancer therapy, radionuclides characteristics, applications, and challenges

S Salih, A Alkatheeri, W Alomaim, A Elliyanti - Molecules, 2022 - mdpi.com
Advances in the field of molecular biology have had an impact on biomedical applications,
which provide greater hope for both imaging and therapeutics. Work has been intensified on …

[HTML][HTML] Extensive preclinical evaluation of lutetium-177-labeled PSMA-specific tracers for prostate cancer radionuclide therapy

EAM Ruigrok, N van Vliet, SU Dalm, E de Blois… - European journal of …, 2021 - Springer
Purpose Various radiolabeled prostate-specific membrane antigen (PSMA)–targeting
tracers are clinically applied for prostate cancer (PCa) imaging and targeted radionuclide …

State of the art in radiolabeling of antibodies with common and uncommon radiometals for preclinical and clinical immuno-PET

M Chomet, GAMS van Dongen… - Bioconjugate chemistry, 2021 - ACS Publications
Inert and stable radiolabeling of monoclonal antibodies (mAb), antibody fragments, or
antibody mimetics with radiometals is a prerequisite for immuno-PET. While radiolabeling is …

A patent review on the current developments of benzoxazoles in drug discovery

XK Wong, KY Yeong - ChemMedChem, 2021 - Wiley Online Library
The benzoxazole moiety is widely found in various natural compounds, which are often
found to be biologically active. Due to its versatile biological properties, benzoxazole has …

[HTML][HTML] Theranostic advances in breast cancer in nuclear medicine

N Vahidfar, A Aghanejad, H Ahmadzadehfar… - International journal of …, 2021 - mdpi.com
The implication of 'theranostic'refers to targeting an identical receptor for diagnostic and
therapeutic purposes, by the same radioligand, simultaneously or separately. In regard to …