Emerging roles of olfactory receptors in glucose metabolism

Z Yang, J Cheng, P Shang, JP Sun, X Yu - Trends in Cell Biology, 2023 - cell.com
Olfactory receptors (ORs) are widely expressed in extra-nasal tissues, where they participate
in the regulation of divergent physiological processes. An increasing body of evidence over …

[HTML][HTML] LGR signaling mediates muscle-adipose tissue crosstalk and protects against diet-induced insulin resistance

O Kubrak, AF Jørgensen, T Koyama, M Lassen… - Nature …, 2024 - nature.com
Obesity impairs tissue insulin sensitivity and signaling, promoting type-2 diabetes. Although
improving insulin signaling is key to reversing diabetes, the multi-organ mechanisms …

Involvement of intestinal flora and miRNA into the mechanism of coarse grains improving type 2 diabetes: an overview

X Deng, L Niu, J Xiao, Q Guo, J Liang… - Journal of the …, 2023 - Wiley Online Library
The prevalence of type 2 diabetes has been growing at an increasing rate worldwide.
Dietary therapy is probably the easiest and least expensive method to prevent and treat …

The effects of aerobic exercise on liver function, insulin resistance, and lipid profiles in prediabetic and type 2 diabetic mice

F Kazeminasab, M Baharlooie, H Rezazadeh… - Physiology & …, 2023 - Elsevier
Background and aims The purpose of the current study was to evaluate the expression of
gluconeogenesis and insulin resistance key genes; including insulin receptor substrate 1 …

Lipidomics in diabetes

EJ Kim, R Ramachandran… - Current Opinion in …, 2022 - journals.lww.com
Lipidomics in diabetes : Current Opinion in Endocrinology, Diabetes and Obesity
Lipidomics in diabetes : Current Opinion in Endocrinology, Diabetes and Obesity Log in or …

Cross talk between insulin and glucagon receptor signaling in the hepatocyte

KM Habegger - Diabetes, 2022 - Am Diabetes Assoc
While the consumption of external energy (ie, feeding) is essential to life, this action induces
a temporary disturbance of homeostasis in an animal. A primary example of this effect is …

[HTML][HTML] Mitochondrial disorders as a mechanism for the development of obese Sarcopenia

T Liao, L Xiong, X Wang, S Yang, Z Liang - Diabetology & Metabolic …, 2023 - Springer
Obese sarcopenia is a severe and prevalent disease in an aging society. Compared to
sarcopenia alone, the development and advanced stage of obesity sarcopenia is faster and …

[HTML][HTML] DPHB, a diarylheptane from Alpinia officinarum Hance, ameliorates insulin resistance: A network pharmacology and in vitro study

X Li, H Wen, Y Zhang, A Liu, X Zhang, M Fu… - Frontiers in …, 2022 - frontiersin.org
(4 E)-7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB) derived from A.
officinarum Hance has been reported to exert anti-inflammatory and anti-insulin resistance …

[PDF][PDF] The Effects of Ketogenic Diet on Insulin Sensitivity and Weight Loss, Which Came First: The Chicken or the Egg? Nutrients 2023, 15, 3120

A Paoli, A Bianco, T Moro, JF Mota… - 2023 - iris.unipa.it
The ketogenic diet (KD) is, nowadays, considered an interesting nutritional approach for
weight loss and improvement in insulin resistance. Nevertheless, most of the studies …

[HTML][HTML] GLP‑1 receptor agonist protects palmitate-induced insulin resistance in skeletal muscle cells by up-regulating sestrin2 to promote autophagy

X Tian, Y Gao, M Kong, L Zhao, E Xing, Q Sun, J He… - Scientific Reports, 2023 - nature.com
In this study, we aimed to determine whether liraglutide could effectively reduce insulin
resistance (IR) by regulating Sestrin2 (SESN2) expression in L6 rat skeletal muscle cells by …