Fertility and infertility: Definition and epidemiology

M Vander Borght, C Wyns - Clinical biochemistry, 2018 - Elsevier
Infertility is a disease characterized by the failure to establish a clinical pregnancy after 12
months of regular and unprotected sexual intercourse. It is estimated to affect between 8 and …

[HTML][HTML] Cardiovascular and metabolic profiles of offspring conceived by assisted reproductive technologies: a systematic review and meta-analysis

XY Guo, XM Liu, L Jin, TT Wang, K Ullah, JZ Sheng… - Fertility and sterility, 2017 - Elsevier
Objective To evaluate cardiovascular and metabolic features of offspring conceived by in
vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI). Design Literature review and …

[HTML][HTML] Homozygous mutations in WEE2 cause fertilization failure and female infertility

Q Sang, B Li, Y Kuang, X Wang, Z Zhang… - The American Journal of …, 2018 - Elsevier
Fertilization is a fundamental process of development and is a prerequisite for successful
human reproduction. In mice, although several receptor proteins have been shown to play …

Environment, lifestyle, and female infertility

R Bala, V Singh, S Rajender, K Singh - Reproductive sciences, 2021 - Springer
Lifestyle factors, which include the practices we adopt in our daily life, have a significant role
in shaping our overall health. These lifestyle choices are mainly centered on personal …

Genetic factors as potential molecular markers of human oocyte and embryo quality

Q Sang, Z Zhou, J Mu, L Wang - Journal of assisted reproduction and …, 2021 - Springer
Successful human reproduction requires gamete maturation, fertilization, and early
embryonic development. Human oocyte maturation includes nuclear and cytoplasmic …

[HTML][HTML] Homozygous mutations in BTG4 cause zygotic cleavage failure and female infertility

W Zheng, Z Zhou, Q Sha, X Niu, X Sun, J Shi… - The American Journal of …, 2020 - Elsevier
Zygotic cleavage failure (ZCF) is a unique early embryonic phenotype resulting in female
infertility and recurrent failure of in vitro fertilization (IVF) and/or intracytoplasmic sperm …

A systematic review on the adverse health effects of di-2-ethylhexyl phthalate

M Zarean, M Keikha, P Poursafa… - … Science and Pollution …, 2016 - Springer
Abstract Di (ethylhexyl) phthalate (DEHP) is a global environmental pollutant. This study
aims to systematically review the literature on health effects of exposure to DEHP including …

Is bisphenol A an environmental obesogen?

S Legeay, S Faure - Fundamental & clinical pharmacology, 2017 - Wiley Online Library
Bisphenol A (BPA) is an endocrine disruptor with an oestrogenic activity that is widely
produced for the manufacture of polycarbonate plastic, epoxy resin, and thermal paper. Its …

A pannexin 1 channelopathy causes human oocyte death

Q Sang, Z Zhang, J Shi, X Sun, B Li, Z Yan… - Science translational …, 2019 - science.org
Connexins and pannexins are two protein families that play an important role in cellular
communication. Pannexin 1 (PANX1), one of the members of pannexin family, is a channel …

Female subfertility

CM Farquhar, S Bhattacharya, S Repping… - Nature reviews Disease …, 2019 - nature.com
Subfertility is common and affects one in six couples, half of whom lack an explanation for
their delay in conceiving. Developments in the diagnosis and treatment of subfertility over …