2020 focused updates to the asthma management guidelines: a report from the National Asthma Education and Prevention Program Coordinating Committee Expert …

MM Cloutier, AP Baptist, KV Blake, EG Brooks… - Journal of Allergy and …, 2020 - Elsevier
The 2020 Focused Updates to the Asthma Management Guidelines: A Report from the
National Asthma Education and Prevention Program Coordinating Committee Expert Panel …

Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update

M Mehta, DS Dhanjal, KR Paudel, B Singh… - …, 2020 - Springer
Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …

Management of severe asthma: a European respiratory society/American thoracic society guideline

F Holguin, JC Cardet, KF Chung, S Diver… - European respiratory …, 2020 - Eur Respiratory Soc
This document provides clinical recommendations for the management of severe asthma.
Comprehensive evidence syntheses, including meta-analyses, were performed to …

Efficacy and safety of once-daily single-inhaler triple therapy (FF/UMEC/VI) versus FF/VI in patients with inadequately controlled asthma (CAPTAIN): a double-blind …

LA Lee, Z Bailes, N Barnes, LP Boulet… - The Lancet …, 2021 - thelancet.com
Background Despite inhaled corticosteroid plus long-acting β 2-agonist (ICS/LABA) therapy,
30–50% of patients with moderate or severe asthma remain inadequately controlled. We …

Severe and difficult-to-treat asthma in adults

E Israel, HK Reddel - New England Journal of Medicine, 2017 - Mass Medical Soc
Severe and Difficult-to-Treat Asthma in Adults | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Asthma exacerbations: pathogenesis, prevention, and treatment

JR Castillo, SP Peters, WW Busse - The Journal of Allergy and Clinical …, 2017 - Elsevier
Guideline-based management of asthma focuses on disease severity and choosing the
appropriate medical therapy to control symptoms and reduce the risk of exacerbations …

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

KF Chung, SE Wenzel, JL Brozek… - European respiratory …, 2014 - Eur Respiratory Soc
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

Japanese guidelines for adult asthma 2020

Y Nakamura, J Tamaoki, H Nagase… - Allergology …, 2020 - jstage.jst.go.jp
abstract Bronchial asthma is characterized by chronic airway inflammation, which manifests
clinically as variable airway narrowing (wheezes and dyspnea) and cough. Long-standing …

Once-daily, single-inhaler mometasone–indacaterol–glycopyrronium versus mometasone–indacaterol or twice-daily fluticasone–salmeterol in patients with …

HAM Kerstjens, J Maspero, KR Chapman… - The Lancet …, 2020 - thelancet.com
Background Patients with asthma who are inadequately controlled on inhaled corticosteroid–
long-acting β 2-adrenoceptor agonist (ICS–LABA) combinations might benefit from the …

Single inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials

JC Virchow, P Kuna, P Paggiaro, A Papi, D Singh… - The Lancet, 2019 - thelancet.com
Background To date, no studies have assessed the efficacy of single-inhaler triple therapy in
asthma. Here we report on two studies that compared the single-inhaler extrafine …