Despite a greater risk of cancer associated with higher BMI, overweight (BMI 25–< 30 kg/m2)
and class I obese (BMI 30–< 35 kg/m2) patients often have a paradoxically lower risk of …

Although overweight/obesity is a major risk factor for the development of type 2 diabetes
mellitus, there is increasing evidence that overweight or obese patients with type 2 diabetes …

Obesity and type 2 diabetes are causally related, yet there is considerable heterogeneity in
the consequences of both conditions and the mechanisms of action are poorly defined. Here …

Background Obesity has been proven to be a risk factor for type 2 diabetes mellitus (T2DM)
through numerous pathogenetic mechanisms. Unexpectedly, some studies suggest that …

OBJECTIVE The obesity paradox in which overweight/obesity is associated with mortality
benefits is believed to be explained by confounding and reverse causality rather than by a …

Cardiovascular disease (CVD) disproportionately affects ethnic minority groups globally.
Ethnic minority groups face particularly high CVD burden and mortality, exacerbated by …

Introduction A body shape index (ABSI) is independently associated with mortality in general
population, but studies on the predictability of ABSI in the risk of mortality in patients with …

Abstract Background Glycosylated hemoglobin (HbA1c) has a detrimental impact on the
myocardium with left ventricular (LV) diastolic dysfunction. Obesity is a risk factor of type 2 …

Background Life-style interventions, including smoking cessation and weight control are of
importance for managing future escalating prevalence of obesity. Smoking habits and …

Aims We evaluated the relationship between body mass index (BMI) and cancer mortality in
incident type 2 diabetes. Methods We used the Clinical Practice Research Datalink GOLD …