Zinc (II)-tetradentate-coordinated probe with aggregation-induced emission characteristics for selective imaging and photoinactivation of bacteria
The emergence of drug-resistant bacterial pathogens highlights an urgent need for new
therapeutic options. Photodynamic therapy (PDT) has emerged as a potential alternative to …
therapeutic options. Photodynamic therapy (PDT) has emerged as a potential alternative to …
Nano-based theranostics for chronic obstructive lung diseases: challenges and therapeutic potential
N Vij - Expert opinion on drug delivery, 2011 - Taylor & Francis
The major challenges in the delivery and therapeutic efficacy of nano-delivery systems in
chronic obstructive airway conditions are airway defense, severe inflammation and mucous …
chronic obstructive airway conditions are airway defense, severe inflammation and mucous …
A simple and effective “capping” approach to readily tune the fluorescence of near-infrared cyanines
Heptamethine cyanines are favorable for fluorescence imaging applications in biological
systems owing to their near-infrared (NIR) absorption and emission. However, it is very …
systems owing to their near-infrared (NIR) absorption and emission. However, it is very …
A near-infrared fluorescence chemodosimeter for fluoride via specific Si–O cleavage
J Cao, C Zhao, W Zhu - Tetrahedron Letters, 2012 - Elsevier
A near-infrared (NIR) fluorescent chemodosimeter for F− was developed on the basis of
dicyanomethylene-4H-chromene derivative, with several merits such as a high off/on ratio …
dicyanomethylene-4H-chromene derivative, with several merits such as a high off/on ratio …
Synthetic membrane active amphiphiles
During the past several decades, various synthetic organic compounds that form pores in
bilayer membranes have been prepared and studied. These membrane active amphiphiles …
bilayer membranes have been prepared and studied. These membrane active amphiphiles …
Fluorescent imaging of bacterial infections and recent advances made with multimodal radiopharmaceuticals
MM Welling, AW Hensbergen, A Bunschoten… - Clinical and …, 2019 - Springer
Background Today, both radioactive SPECT and PET imaging radiopharmaceuticals are
used for clinical diagnosis of bacterial infections. Due to the possible applications in image …
used for clinical diagnosis of bacterial infections. Due to the possible applications in image …
π-Conjugated cyanostilbene-based optoelectric functional materials
C Hang, HW Wu, LL Zhu - Chinese Chemical Letters, 2016 - Elsevier
Abstract π-Conjugated organic luminescent materials are essential components for modern
optical and photoelectric research. This review mainly probes into the recent work in the …
optical and photoelectric research. This review mainly probes into the recent work in the …
β‐Lactam antibiotics
SA Testero, JF Fisher… - … medicinal chemistry and …, 2003 - Wiley Online Library
The β‐lactam classes of antibacterials are preeminent in the treatment of bacterial infection
due to their unparalleled clinical efficacy and clinical safety. Following the discovery of the …
due to their unparalleled clinical efficacy and clinical safety. Following the discovery of the …
In vivo targeting of cell death using a synthetic fluorescent molecular probe
BA Smith, S Xiao, W Wolter, J Wheeler, MA Suckow… - Apoptosis, 2011 - Springer
A synthetic, near-infrared, fluorescent probe, named PSS-794 was assessed for its ability to
detect cell death in two animal models. The molecular probe contains a zinc (II) …
detect cell death in two animal models. The molecular probe contains a zinc (II) …
Lysosomal pH decrease in inflammatory cells used to enable activatable imaging of inflammation with a sialic acid conjugated profluorophore
Inflammation causes significant morbidity and mortality, necessitating effective in vivo
imaging of inflammation. Prior approaches often rely on combination of optical agents with …
imaging of inflammation. Prior approaches often rely on combination of optical agents with …