Irrespective of the reason for hypoperfusion, hypocoagulable and/or hyperfibrinolytic
hemostatic aberrancies afflict up to one-quarter of critically ill patients in shock. Intensivists …

Uncontrolled bleeding is the leading cause of preventable death following injury. Trauma-
induced coagulopathy can manifest as diverse phenotypes ranging from hypocoagulability …

Background: The incidence of coagulopathy after open traumatic brain injury (TBI) is high.
Coagulopathy can aggravate intracranial hemorrhage and further increase morbidity and …

The assessment of hemostatic disorders in neonates is crucial, but remains challenging for
clinicians. Although the concept of developmental hemostasis is widely accepted among …

Background: Because of the aging population, the number of low falls in elderly people with
pre-existing anticoagulation is rising, often leading to traumatic brain injury (TBI) with a …

Objective Traumatic brain injury (TBI) leads to death and disability. This study developed an
effective prognostic nomogram for assessing the risk factors for TBI mortality. Method Data …

The expression “developmental hemostasis” indicates the age-related physiological
changes occurring during the maturational process of the hemostatic system. Despite the …

Modern approaches to resuscitation seek to bring patient interventions as close as possible
to the initial trauma. In recent decades, fresh or cold-stored whole blood has gained …

Introduction Coagulopathy associated with isolated traumatic brain injury (C-iTBI) is a
frequent complication associated with poor outcomes, primarily due to its role in the …

Coagulopathy and traumatic brain injury (TBI) are complexly intertwined. In isolated TBI,
coagulopathy may contribute to hemorrhagic lesion development, progression, or …