Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections
The incidence rates of sexually transmitted infections (STIs), including the four major curable
STIs–chlamydia, gonorrhea, trichomoniasis and, syphilis–continue to increase globally …
STIs–chlamydia, gonorrhea, trichomoniasis and, syphilis–continue to increase globally …
“Sample-to-answer” detection of rare ctDNA mutation from 2 mL plasma with a fully integrated DNA extraction and digital droplet PCR microdevice for liquid biopsy
Z Geng, S Li, L Zhu, Z Cheng, M Jin, B Liu… - Analytical …, 2020 - ACS Publications
The “sample-to-answer” integration and automation of circulating tumor DNA (ctDNA)-based
liquid biopsy using digital PCR (dPCR) has been hampered by the complicated operations …
liquid biopsy using digital PCR (dPCR) has been hampered by the complicated operations …
An ultrasensitive and rapid “sample-to-answer” microsystem for on-site monitoring of SARS-CoV-2 in aerosols using “in situ” tetra-primer recombinase polymerase …
Airborne transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has highlighted the urgent need for aerosol monitoring of SARS-CoV-2 to prevent sporadic …
has highlighted the urgent need for aerosol monitoring of SARS-CoV-2 to prevent sporadic …
One-Stop Extraction and In Situ RT-qPCR for Ultrasensitive Detection of Highly Diluted SARS-CoV-2 in Large-Volume Samples from Aquatic Environments
Surveillance of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in aquatic
environments attracted attention due to its considerable impacts on human health and …
environments attracted attention due to its considerable impacts on human health and …
A fully integrated nucleic acid analysis system for multiplex detection of genetic polymorphisms related to folic acid metabolism
B Lin, Z Geng, Y Chen, W Zeng, B Li, Y Zhang, P Liu - Lab on a Chip, 2023 - pubs.rsc.org
A sufficient intake of folic acid is essential during pregnancy, but several genetic
polymorphisms reduce its absorption, threaten the lives of pregnant women and cause …
polymorphisms reduce its absorption, threaten the lives of pregnant women and cause …
A scalable microfluidic chamber array for sample-loss-free and bubble-proof sample compartmentalization by simple pipetting
Sample compartmentalization is a pivotal technique in many bioanalytical applications, such
as multiplex polymerase chain reaction (PCR) and digital PCR (dPCR). In this study, we …
as multiplex polymerase chain reaction (PCR) and digital PCR (dPCR). In this study, we …
A gamepad-like nucleic acid testing device for rapid detection of SARS-CoV-2 via visible nested recombinase polymerase amplification
C Liu, B Lin, G Yuan, Z Geng, Z Zhao, J Wang… - Communications …, 2024 - nature.com
Nucleic acid tests are essential for the accurate diagnosis and control of infectious diseases.
However, current assays are not easily scalable for a large population, due to the …
However, current assays are not easily scalable for a large population, due to the …
Fully automated system for rapid enrichment and precise detection of enterobacteria using magneto-electrochemical impedance measurements
The contamination of food and drinking water by bacteria that cause food poisoning is a
critical public health issue. In general, the procedures for testing the presence of pathogenic …
critical public health issue. In general, the procedures for testing the presence of pathogenic …
Miniaturized platform for individual coral polyps culture and monitoring
Y Luo, J Zhao, C He, Z Lu, X Lu - Micromachines, 2020 - mdpi.com
Methodologies for coral polyps culture and real-time monitoring are important in
investigating the effects of the global environmental changes on coral reefs and marine …
investigating the effects of the global environmental changes on coral reefs and marine …
Needle-Plug/Piston-Based Modular Mesoscopic Design Paradigm Coupled with Microfluidic Device for Point-of-Care Pooled Testing
B Lin, B Li, W Zeng, Y Zhao, H Li, Y Gu, P Liu - medRxiv, 2024 - medrxiv.org
Emerging diagnostic scenarios, such as population surveillance by pooled testing and on-
site rapid diagnosis, highlight the importance of advanced microfluidic systems for in vitro …
site rapid diagnosis, highlight the importance of advanced microfluidic systems for in vitro …