Epithelial–mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis

T Chen, Y You, H Jiang, ZZ Wang - Journal of cellular …, 2017 - Wiley Online Library
The lineage transition between epithelium and mesenchyme is a process known as
epithelial–mesenchymal transition (EMT), by which polarized epithelial cells lose their …

Concise review: MSC adhesion cascade—insights into homing and transendothelial migration

F Nitzsche, C Müller, B Lukomska, J Jolkkonen… - Stem …, 2017 - academic.oup.com
Mesenchymal stem cells (MSCs) are promising candidates for adult cell therapies in
regenerative medicine. To fully exert their potential, efficient homing and migration toward …

[HTML][HTML] Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis

S Cosenza, K Toupet, M Maumus, P Luz-Crawford… - Theranostics, 2018 - ncbi.nlm.nih.gov
Objectives: Mesenchymal stem cells (MSCs) release extracellular vesicles (EVs) that display
a therapeutic effect in inflammatory disease models. Although MSCs can prevent arthritis …

Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

[HTML][HTML] Adipose-derived stem cells: effectiveness and advances in delivery in diabetic wound healing

M Gadelkarim, AI Abushouk, E Ghanem… - Biomedicine & …, 2018 - Elsevier
With the increasing global prevalence of diabetes mellitus, a significant rise in the number of
patients suffering from non-healing wounds is expected. However, available treatments …

[HTML][HTML] Mesenchymal stem cell-based therapy and exosomes in COVID-19: current trends and prospects

M Abdelgawad, NS Bakry, AA Farghali… - Stem cell research & …, 2021 - Springer
Abstract Novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus-2. The virus causes an exaggerated immune response, resulting in a …

[HTML][HTML] Amniotic membrane mesenchymal cells-derived factors skew T cell polarization toward Treg and downregulate Th1 and Th17 cells subsets

S Pianta, P Bonassi Signoroni, I Muradore… - Stem Cell Reviews and …, 2015 - Springer
We previously demonstrated that cells derived from the mesenchymal layer of the human
amniotic membrane (hAMSC) and their conditioned medium (CM-hAMSC) modulate …

Microsphere–Gel Composite System with Mesenchymal Stem Cell Recruitment, Antibacterial, and Immunomodulatory Properties Promote Bone Regeneration via …

S Ma, C Wang, Y Dong, W Jing, P Wei… - … Applied Materials & …, 2022 - ACS Publications
Various types of biomaterials have been widely used to treat complex bone defects.
However, potential infection risks and inappropriate host immune responses induced by …

[HTML][HTML] Adipose-derived stem cells improve tendon repair and prevent ectopic ossification in tendinopathy by inhibiting inflammation and inducing neovascularization …

S Kokubu, R Inaki, K Hoshi, A Hikita - Regenerative therapy, 2020 - Elsevier
Introduction Achilles tendinopathy is characterized by scar formation or ectopic ossification,
both of which result in pain and worsened physical function in athletes and older people …

[HTML][HTML] Overexpression of CXCR7 promotes mesenchymal stem cells to repair phosgene-induced acute lung injury in rats

Y Shao, F Zhou, D He, L Zhang, J Shen - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Phosgene exposure may result in acute lung injury (ALI) with high mortality. Emerging
evidence suggests that mesenchymal stem cells (MSCs) have a therapeutic potential …