The capsule of the fungal pathogen Cryptococcus neoformans
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …
in recent decades and a large body of information is now available to the scientific …
Virulence factors of medically important fungi
Human fungal pathogens have become an increasingly important medical problem with the
explosion in the number of immunocompromised patients as a result of cancer, steroid …
explosion in the number of immunocompromised patients as a result of cancer, steroid …
Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans
CA D'Souza, JA Alspaugh, C Yue… - … and cellular biology, 2001 - Am Soc Microbiol
Cryptococcus neoformans is an opportunistic fungal pathogen that infects the human central
nervous system. This pathogen elaborates two specialized virulence factors: the antioxidant …
nervous system. This pathogen elaborates two specialized virulence factors: the antioxidant …
Conserved cAMP signaling cascades regulate fungal development and virulence
CA D'Souza, J Heitman - FEMS microbiology reviews, 2001 - academic.oup.com
Two well characterized signal transduction cascades regulating fungal development and
virulence are the MAP kinase and cAMP signaling cascades. Here we review the current …
virulence are the MAP kinase and cAMP signaling cascades. Here we review the current …
Experimental modulation of capsule size in Cryptococcus neoformans
O Zaragoza, A Casadevall - Biological procedures online, 2004 - Springer
Experimental modulation of capsule size is an important technique for the study of the
virulence of the encapsulated pathogen Cryptococcus neoformans. In this paper, we …
virulence of the encapsulated pathogen Cryptococcus neoformans. In this paper, we …
Cryptococcosis in apparently immunocompetent patients
Background: Few reports have described the clinical and microbiological features of
cryptococcosis in immunocompetent patients. Aim: To compare clinical presentations and …
cryptococcosis in immunocompetent patients. Aim: To compare clinical presentations and …
Phase I evaluation of the safety and pharmacokinetics of murine-derived anticryptococcal antibody 18B7 in subjects with treated cryptococcal meningitis
RA Larsen, PG Pappas, J Perfect… - Antimicrobial agents …, 2005 - Am Soc Microbiol
ABSTRACT A promising approach to improving outcomes in patients with cryptococcal
meningitis is to use adjunctive passive immunotherapy with a monoclonal antibody (MAb) …
meningitis is to use adjunctive passive immunotherapy with a monoclonal antibody (MAb) …
Induction of Capsule Growth in Cryptococcus neoformans by Mammalian Serum and CO2
O Zaragoza, BC Fries, A Casadevall - Infection and immunity, 2003 - Am Soc Microbiol
The pathogenic fungus Cryptococcus neoformans has a polysaccharide capsule that is
essential for virulence in vivo. Capsule size is known to increase during animal infection …
essential for virulence in vivo. Capsule size is known to increase during animal infection …
Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …
disease. These fungi commonly enter their host via inhalation into the lungs where they …