Thalassaemia is a diverse group of genetic disorders with a worldwide distribution affecting
globin chain synthesis. The pathogenesis of thalassaemia lies in the unbalanced globin …

Post-transfusion alloimmunisation is the main complication of all those observed after one or
more transfusion episodes. Alloimmunisation is observed after the transfusion of red blood …

The observed specificity of β-thalassemia-subtype phenotypes makes new diagnostic
strategies that complement current screening methods necessary to determine each subtype …

Background Alloimmunization prevalence is conventionally used to identify RBCs
alloimmunization risk factors among thalassemia patients, but it may be confounded by …

The development of erythrocyte alloantibodies complicates transfusion therapy in β
thalassemia major patients. These antibodies increase the need for blood and intensify …

Background Thalassemia is a common genetic disease in Southeast Asia. Red blood cell
(RBC) transfusion is an essential treatment for severe forms of thalassemia. We performed a …

Background Alloimmunisation remains a major consequence of blood transfusion among
sickle cell disease (SCD) and thalassemia patients due to the exposure to non-self-red …

Background: When the COVID-19 epidemic occurred for the first time in December 2019, the
governments worldwide took some restriction measures for slowing the spread of novel …

Background Red blood cell (RBC) alloimmunization (AI) is a well‐known complication of
RBC transfusions, which results in the formation of alloantibodies to non‐self antigens on …

Background Transfusion‐dependent thalassemia patients are at high risk of transfusion‐
related complications. Yet, there is scanty data on the frequency of transfusion reactions …