[HTML][HTML] Biology of Pellino1: a potential therapeutic target for inflammation in diseases and cancers

L Yan, Y Cui, J Feng - Frontiers in Immunology, 2023 - frontiersin.org
Pellino1 (Peli1) is a highly conserved E3 Ub ligase that exerts its biological functions by
mediating target protein ubiquitination. Extensive evidence has demonstrated the crucial …

A review and analysis of key biomarkers in Alzheimer's disease

Z Zhang, X Liu, S Zhang, Z Song, K Lu… - Frontiers in …, 2024 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects over 50
million elderly individuals worldwide. Although the pathogenesis of AD is not fully …

Atypical dynamic network reconfiguration and genetic mechanisms in patients with major depressive disorder

H Xiao, D Tang, C Zheng, Z Yang, W Zhao… - Progress in Neuro …, 2024 - Elsevier
Background Brain dynamics underlie complex forms of flexible cognition or the ability to shift
between different mental modes. However, the precise dynamic reconfiguration based on …

Navigating the Gene Co-Expression Network and Drug Repurposing Opportunities for Brain Disorders Associated with Neurocognitive Impairment

MTA Manuel, LL Tayo - Brain Sciences, 2023 - mdpi.com
Neurocognitive impairment refers to a spectrum of disorders characterized by a decline in
cognitive functions such as memory, attention, and problem-solving, which are often linked …

Integrating Multi-omics Data for Alzheimer's Disease to Explore Its Biomarkers Via the Hypergraph-Regularized Joint Deep Semi-Non-Negative Matrix Factorization …

K Tu, W Zhou, S Kong - Journal of Molecular Neuroscience, 2024 - Springer
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder. Its
etiology may be associated with genetic, environmental, and lifestyle factors. With the …