San-Huang-Xie-Xin-Tang constituents exert drug-drug interaction of mutual reinforcement at both pharmacodynamics and pharmacokinetic level: a review

J Wu, Y Hu, L Xiang, S Li, Y Yuan, X Chen… - Frontiers in …, 2016 - frontiersin.org
Inflammatory disorders underlie varieties of human diseases. San-Huang-Xie-xin-Tang
(SHXXT), composed with Rhizoma Rhei (Rheum palmatum L.), Rhizoma Coptidis (Coptis …

[HTML][HTML] Protective effects of emodin on subchondral bone and articular cartilage in osteoporotic osteoarthritis rats: A preclinical study

Y Wei, J Kang, Z Ma, T Liao, P Wu, P Wang… - Experimental …, 2024 - Elsevier
Abstract Background Osteoporotic osteoarthritis (OP-OA) is a severe pathological form of
OA, urgently requiring precise management strategies and more efficient interventions …

Use of physcion to improve atopic dermatitis-like skin lesions through blocking of thymic stromal lymphopoietin

PD Moon, NR Han, JS Lee, S Hong, MS Yoo, HJ Kim… - Molecules, 2019 - mdpi.com
Physcion is well known for the treatment of carcinoma. However, the therapeutic effect of
physcion on atopic dermatitis (AD) through the inhibition of thymic stromal lymphopoietin …

Physcion protects against ethanol-induced liver injury by reprogramming of circadian clock

Y Yao, A Zuo, Q Deng, S Liu, T Zhan, M Wang… - Frontiers in …, 2020 - frontiersin.org
The circadian clock plays a key role in our daily physiology and metabolism. Alcohol
consumption disrupts the circadian rhythm of metabolic genes in the liver; however, the …

Novel potential agents for ulcerative colitis by molecular topology: suppression of IL-6 production in Caco-2 and RAW 264.7 cell lines

M Galvez-Llompart, M del Carmen Recio Iglesias… - Molecular …, 2013 - Springer
Ulcerative colitis (UC) is an immune-mediated chronic and relapsing intestinal inflammatory
disease. Interleukin (IL)-6, a pro-inflammatory cytokine, plays a key role in the uncontrolled …

Cytopiloyne, a polyacetylenic glucoside from Bidens pilosa, acts as a novel anticandidal agent via regulation of macrophages

CY Chung, WC Yang, CL Liang, HY Liu, SK Lai… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Bidens pilosa, a tropical and sub-tropical herbal plant, is
used as an ethnomedicine for bacterial infection or immune modulation in Asia, America and …

A comprehensive review of traditional uses, phytochemistry and pharmacology of Reynoutria genus

ZL Zhang, YZ Li, GQ Wu, DD Zhang… - Journal of Pharmacy …, 2022 - academic.oup.com
Abstract Objectives The genus Reynoutria belonging to the family Polygonaceae is widely
distributed in the north temperate zone and used in folk medicine. It is administered as a …

Inhibition of DNA topoisomerases I and II of compounds from Reynoutria japonica

K Hwangbo, MS Zheng, YJ Kim, JY Im, CS Lee… - Archives of pharmacal …, 2012 - Springer
Abstract Three anthraquinones (1, 2 and 4), three stilbenes (5, 6 and 7) and 3, 5-
dihydroxybenzyl alcohol (3) were isolated from Reynoutria japonica. Their structures were …

Comparative pharmacokinetic analysis of six major bioactive constituents using UPLC-MS/MS in samples isolated from normal and diabetic nephropathy rats after oral …

L Zhang, C Yang, Y Zhao, Z Yang, X Meng… - Journal of Pharmaceutical …, 2023 - Elsevier
Abstract Berberine, palmatine, physcion, rhein, calycosin-7-O-glucoside, and ferulic acid are
six major active consituents that are present in Gushen Jiedu capsule (GSJD) extracts. The …

[HTML][HTML] A randomized double blinded placebo controlled clinical trial for the evaluation of green coffee extract on immune health in healthy adults

J Narayanaperumal, A D'souza, A Miriyala… - Journal of Traditional …, 2022 - Elsevier
Background The immune system functions to protect the host from a broad array of infectious
diseases. Here, we evaluated the in vitro immunomodulatory effects of green coffee extract …