Untangling the interdependency of infections, immunity and frailty may help to clarify their
roles in the maintenance of health in aging individuals, and the recent COVID-19 pandemic …

Background Streptococcus pneumoniae (pneumococcus) can cause serious illness,
including sepsis, meningitis, and pneumonia with bacteremia (invasive) or without …

We performed a systematic literature review in PubMed and Embase (2016–2021) to
investigate the drivers of and barriers to routine vaccination in adults aged 50 and older …

Background Ten-valent pneumococcal conjugate vaccine (PCV10), delivered at 6, 10, and
14 weeks of age was introduced in Kenya in January, 2011, accompanied by a catch-up …

Given our global interconnectedness, the COVID-19 pandemic highlights the urgency of
building a global system that can support both routine and pandemic/epidemic adult …

Malaria-elimination interventions aim to extinguish hotspots and prevent transmission to
nearby areas. Here, we re-analyzed a cluster-randomized trial of reactive, focal interventions …

Introduction: Pneumococcal conjugate vaccine (PCV) impact studies have reported
substantial reductions in the incidence of invasive pneumococcal disease (IPD) after …

Streptococcus pneumoniae continues to cause significant disease burden. Whilst
pneumococcal conjugate vaccines (PCV) have substantially reduced this burden, serotype …

At present, the dramatic rise in antimicrobial resistance (AMR) among important human
bacterial pathogens is reaching a state of global crisis threatening a return to the pre …

The importance of Streptococcus pneumoniae has been well established. These bacteria
can colonize infants and adults without symptoms, but in some cases can spread, invade …