Blood reflects tissue oxidative stress depending on biomarker and tissue studied
This study investigated whether selected oxidative stress markers measured in blood
adequately reflect redox status in skeletal muscle, heart, and liver. Several markers were …
adequately reflect redox status in skeletal muscle, heart, and liver. Several markers were …
Plasma oxidative stress parameters in men and women with early stage Alzheimer type dementia
MC Puertas, JM Martinez-Martos, MP Cobo… - Experimental …, 2012 - Elsevier
It is well known that oxidative stress is one of the earliest events in Alzheimer's disease
pathogenesis, indicating that may play a key role in this disease. In our study, we measured …
pathogenesis, indicating that may play a key role in this disease. In our study, we measured …
Glutathione relates to neuropsychological functioning in mild cognitive impairment
Background Mild cognitive impairment (MCI) represents an at-risk state for Alzheimer's
disease in which underlying pathophysiological mechanisms could be delineated. Oxidative …
disease in which underlying pathophysiological mechanisms could be delineated. Oxidative …
S-glutathionylation and S-nitrosylation in mitochondria: Focus on homeostasis and neurodegenerative diseases
S Vrettou, B Wirth - International Journal of Molecular Sciences, 2022 - mdpi.com
Redox post-translational modifications are derived from fluctuations in the redox potential
and modulate protein function, localization, activity and structure. Amongst the oxidative …
and modulate protein function, localization, activity and structure. Amongst the oxidative …
[HTML][HTML] Effects of dietary food components on cognitive functions in older adults
H Ozawa, T Miyazawa, T Miyazawa - Nutrients, 2021 - mdpi.com
Population aging has recently been an important issue as the number of elderly people is
growing worldwide every year, and the extension of social security costs is financially costly …
growing worldwide every year, and the extension of social security costs is financially costly …
Potentiation of glutathione loss and nerve cell death by the transition metals iron and copper: Implications for age-related neurodegenerative diseases
P Maher - Free Radical Biology and Medicine, 2018 - Elsevier
There is growing evidence for alterations in iron and copper homeostasis during aging that
are exacerbated in neurodegenerative diseases such as Alzheimer's disease (AD) …
are exacerbated in neurodegenerative diseases such as Alzheimer's disease (AD) …
Quantitation of in vivo brain glutathione conformers in cingulate cortex among age‐matched control, MCI, and AD patients using MEGA‐PRESS
D Shukla, PK Mandal, M Tripathi… - Human brain …, 2020 - Wiley Online Library
Oxidative stress (OS) plays an important role in Alzheimer's disease (AD) and glutathione
(GSH) mitigates this effect by maintaining redox‐imbalance and free‐radical neutralization …
(GSH) mitigates this effect by maintaining redox‐imbalance and free‐radical neutralization …
Glutathione: an old and small molecule with great functions and new applications in the brain and in Alzheimer's disease
M Haddad, V Hervé, MR Ben Khedher… - Antioxidants & Redox …, 2021 - liebertpub.com
Significance: Glutathione (GSH) represents the most abundant and the main antioxidant in
the body with important functions in the brain related to Alzheimer's disease (AD). Recent …
the body with important functions in the brain related to Alzheimer's disease (AD). Recent …
Cognitive improvement with glutathione supplement in Alzheimer's disease: a way forward
PK Mandal, D Shukla, M Tripathi… - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder affecting millions of
people worldwide. The actual cause of AD is still unknown. Oxidative stress is believed to be …
people worldwide. The actual cause of AD is still unknown. Oxidative stress is believed to be …
Ferroptosis and neurodegenerative diseases: Insights into the regulatory roles of SLC7A11
C Wang, H Liu, S Xu, Y Deng, B Xu, T Yang… - Cellular and Molecular …, 2023 - Springer
Programed cell death plays a key role in promoting human development and maintaining
homeostasis. Ferroptosis is a recently identified pattern of programmed cell death that is …
homeostasis. Ferroptosis is a recently identified pattern of programmed cell death that is …