Schizophrenia is a severe psychiatric illness affecting almost 25 million people worldwide
and is conceptualized as a disorder of synaptic plasticity and brain connectivity …

Although the dopamine hypothesis of schizophrenia explains the effects of all the available
antipsychotics in clinical use, there is an increasing need for developing new drugs for the …

Background The neurobiology of treatment-resistant schizophrenia (TRS) is poorly
understood, and meta-analytic consensus regarding magnetic resonance spectroscopic …

Trace amines and their receptors are a family of G protein-coupled receptors widely
distributed in the central nervous system and periphery. The trace amine-associated …

精神分裂症是临床常见的精神疾病之一, 以思维, 行为, 情感障碍, 精神活动不协调为主要临床
表现, 具有病情迁延, 复发率高, 预后差等特点, 临床多采用药物治疗, 控制患者病情 …

Schizophrenia and schizoaffective disorder are generally treated with second-generation
antipsychotic drugs. These drugs are mostly D2 and 5-HT2A antagonists. They improve …

Background and objective: Schizophrenia is associated with considerable functional
impairment and high rates of treatment failure due to the variable effect of treatment …