The protective role of estrogen and estrogen receptors in cardiovascular disease and the controversial use of estrogen therapy
Epidemiologic studies have previously suggested that premenopausal females have
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …
Mitochondria: a central target for sex differences in pathologies
R Ventura-Clapier, M Moulin, J Piquereau… - Clinical …, 2017 - portlandpress.com
It is increasingly acknowledged that a sex and gender specificity affects the occurrence,
development, and consequence of a plethora of pathologies. Mitochondria are considered …
development, and consequence of a plethora of pathologies. Mitochondria are considered …
[HTML][HTML] Uncovering sex-specific mechanisms of action of testosterone and redox balance
D Cruz-Topete, P Dominic, KY Stokes - Redox Biology, 2020 - Elsevier
The molecular and pharmacological manipulation of the endogenous redox system is a
promising therapy to limit myocardial damage after a heart attack; however, antioxidant …
promising therapy to limit myocardial damage after a heart attack; however, antioxidant …
Sex‐based differences in cardiac ischaemic injury and protection: therapeutic implications
B Ostadal, P Ostadal - British journal of pharmacology, 2014 - Wiley Online Library
Ischaemic heart disease (IHD) is the most frequent cause of mortality among men and
women. Many epidemiological studies have demonstrated that premenopausal women …
women. Many epidemiological studies have demonstrated that premenopausal women …
Photobiomodulation: evolution and adaptation
NB Lipko - Photobiomodulation, Photomedicine, and Laser …, 2022 - liebertpub.com
Photobiomodulation (PBM) can be described as the intentional use of low-power laser or
light-emitting diode light in the visible and near-infrared light spectra as a medical treatment …
light-emitting diode light in the visible and near-infrared light spectra as a medical treatment …
Significant role of estrogen in maintaining cardiac mitochondrial functions
C Rattanasopa, S Phungphong… - The Journal of steroid …, 2015 - Elsevier
Increased susceptibility to stress-induced myocardial damage is a significant concern in
addition to decreased cardiac performance in postmenopausal females. To determine the …
addition to decreased cardiac performance in postmenopausal females. To determine the …
Testosterone deficiency impairs cardiac interfibrillar mitochondrial function and myocardial contractility while inducing oxidative stress
PR do Val Lima, KS Ronconi, EA Morra… - Frontiers in …, 2023 - frontiersin.org
Introduction Clinical studies have shown that low levels of endogenous testosterone are
associated with cardiovascular diseases. Considering the intimate connection between …
associated with cardiovascular diseases. Considering the intimate connection between …
Long-term inorganic nitrate administration protects against myocardial ischemia-reperfusion injury in female rats
Background The favorable effects of nitrate against myocardial ischemia-reperfusion injury
(MIRI) have primarily focused on male rats and in short term. Here we determine the impact …
(MIRI) have primarily focused on male rats and in short term. Here we determine the impact …
Apoptosis and autophagy contribute to gender difference in cardiac ischemia–reperfusion induced injury in rats
C Chen, LX Hu, T Dong, GQ Wang, LH Wang, XP Zhou… - Life sciences, 2013 - Elsevier
Aims Gender difference in cardiac ischemia–reperfusion (IR) induced injury has been
reported in animal models. However, a large-scale clinical trial found an increase in …
reported in animal models. However, a large-scale clinical trial found an increase in …
Sex difference in cardioprotection against acute myocardial infarction in MAO-B knockout mice in vivo
J Heger, T Szabados, P Brosinsky, P Bencsik… - International Journal of …, 2023 - mdpi.com
The cardiomyocyte-specific knockout (KO) of monoamine oxidase (MAO)-B, an enzyme
involved in the formation of reactive oxygen species (ROS), reduced myocardial …
involved in the formation of reactive oxygen species (ROS), reduced myocardial …