The β cell in diabetes: integrating biomarkers with functional measures
SE Kahn, YC Chen, N Esser, AJ Taylor… - Endocrine …, 2021 - academic.oup.com
The pathogenesis of hyperglycemia observed in most forms of diabetes is intimately tied to
the islet β cell. Impairments in propeptide processing and secretory function, along with the …
the islet β cell. Impairments in propeptide processing and secretory function, along with the …
Genetic risk factors and gene–lifestyle interactions in gestational diabetes
T Jääskeläinen, MM Klemetti - Nutrients, 2022 - mdpi.com
Paralleling the increasing trends of maternal obesity, gestational diabetes (GDM) has
become a global health challenge with significant public health repercussions. In addition to …
become a global health challenge with significant public health repercussions. In addition to …
Genetic studies of gestational diabetes and glucose metabolism in pregnancy
Abstract Purpose of Review In this review, we summarize studies investigating genetics of
gestational diabetes mellitus (GDM) and glucose metabolism in pregnancy. We describe …
gestational diabetes mellitus (GDM) and glucose metabolism in pregnancy. We describe …
Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes
Aims/hypothesis The aim of this study was to assess the interaction between genetic risk
and lifestyle intervention on the occurrence of gestational diabetes mellitus (GDM) and …
and lifestyle intervention on the occurrence of gestational diabetes mellitus (GDM) and …
Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations
M Li, ML Rahman, J Wu, M Ding, JE Chavarro… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Objective Women with a history of gestational diabetes mellitus (GDM) have an
exceptionally high risk for type 2 diabetes (T2D). Yet, little is known about genetic …
exceptionally high risk for type 2 diabetes (T2D). Yet, little is known about genetic …
Genetics and Epigenetics: Implications for the Life Course of Gestational Diabetes
WL Lowe Jr - International journal of molecular sciences, 2023 - mdpi.com
Gestational diabetes (GDM) is one of the most common complications of pregnancy,
affecting as many as one in six pregnancies. It is associated with both short-and long-term …
affecting as many as one in six pregnancies. It is associated with both short-and long-term …
Prevention of diabetes through lifestyle intervention: lessons learned from the diabetes prevention program and outcomes study and its translation to practice
MA Hoskin, GA Bray, K Hattaway… - Current nutrition …, 2014 - Springer
A number of strategies have been used to delay or prevent the development of type 2
diabetes mellitus (T2D) in high-risk adults, such as diet, exercise, medications, and surgery …
diabetes mellitus (T2D) in high-risk adults, such as diet, exercise, medications, and surgery …
[HTML][HTML] Preexisting diabetes and pregnancy
JL Kitzmiller, A Ferrara, T Peng, MA Cissell, C Kim - 2021 - europepmc.org
The prevalence of diabetes in adolescents and women of reproductive age has increased
since 1995. However, no prospective national population-based data from the United States …
since 1995. However, no prospective national population-based data from the United States …
Effects of treatment with metformin and/or sitagliptin on beta‐cell function and insulin resistance in prediabetic women with previous gestational diabetes
Aim To investigate the effect of sitagliptin (SITA) and metformin (MET) monotherapy as well
as in combination (MET+ SITA) on beta‐cell function and insulin sensitivity in women with …
as in combination (MET+ SITA) on beta‐cell function and insulin sensitivity in women with …
Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus
RB Prasad, K Kristensen, A Katsarou, N Shaat - BMC Medical Genomics, 2021 - Springer
Background This study investigated whether single nucleotide polymorphisms (SNPs)
reported by previous genome-wide association studies (GWAS) to be associated with …
reported by previous genome-wide association studies (GWAS) to be associated with …