Can intracellular Staphylococcus aureus in osteomyelitis be treated using current antibiotics? A systematic review and narrative synthesis
Approximately 40% of treatments of chronic and recurrent osteomyelitis fail in part due to
bacterial persistence. Staphylococcus aureus, the predominant pathogen in human …
bacterial persistence. Staphylococcus aureus, the predominant pathogen in human …
Staphylococcal trafficking and infection—from 'nose to gut'and back
EJM Raineri, D Altulea… - FEMS microbiology …, 2022 - academic.oup.com
Staphylococcus aureus is an opportunistic human pathogen, which is a leading cause of
infections worldwide. The challenge in treating S. aureus infection is linked to the …
infections worldwide. The challenge in treating S. aureus infection is linked to the …
Intracellular Staphylococcus aureus persisters upon antibiotic exposure
F Peyrusson, H Varet, TK Nguyen, R Legendre… - Nature …, 2020 - nature.com
Bacterial persister cells are phenotypic variants that exhibit a transient non-growing state
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …
Antibacterial biomaterials in bone tissue engineering
ZY Chen, S Gao, YW Zhang, RB Zhou… - Journal of Materials …, 2021 - pubs.rsc.org
Bone infection is a devastating disease characterized by recurrence, drug-resistance, and
high morbidity, that has prompted clinicians and scientists to develop novel approaches to …
high morbidity, that has prompted clinicians and scientists to develop novel approaches to …
Staphylococcus aureus populations from the gut and the blood are not distinguished by virulence traits—a critical role of host barrier integrity
EJM Raineri, S Maaß, M Wang, S Brushett… - Microbiome, 2022 - Springer
Abstract Background The opportunistic pathogen Staphylococcus aureus is an
asymptomatically carried member of the microbiome of about one third of the human …
asymptomatically carried member of the microbiome of about one third of the human …
Intracellular Habitation of Staphylococcus aureus: Molecular Mechanisms and Prospects for Antimicrobial Therapy
JW Hommes, BGJ Surewaard - Biomedicines, 2022 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a global health threat,
especially with the continuous development of antibiotic resistance. As an opportunistic …
especially with the continuous development of antibiotic resistance. As an opportunistic …
In or out: Phagosomal escape of Staphylococcus aureus
A Moldovan, MJ Fraunholz - Cellular microbiology, 2019 - Wiley Online Library
Staphylococcus aureus is internalised by host cells in vivo, and recent research results
suggest that the bacteria use this intracellularity to persist in the host and form a reservoir for …
suggest that the bacteria use this intracellularity to persist in the host and form a reservoir for …
Intracellular Staphylococcus aureus in bone and joint infections: a mechanism of disease recurrence, inflammation, and bone and cartilage destruction
Bone and joint infections are devastating afflictions. Although medical interventions and
advents have improved their care, bone and joint infections still portend dismal outcomes …
advents have improved their care, bone and joint infections still portend dismal outcomes …
Streptococcus agalactiae cadD alleviates metal stress and promotes intracellular survival in macrophages and ascending infection during pregnancy
ML Korir, RS Doster, J Lu, MA Guevara… - Nature …, 2022 - nature.com
Perinatal infection with Streptococcus agalactiae, or Group B Streptococcus (GBS), is
associated with preterm birth, neonatal sepsis, and stillbirth. Here, we study the interactions …
associated with preterm birth, neonatal sepsis, and stillbirth. Here, we study the interactions …
Multiple alternative carbon pathways combine to promote Candida albicans stress resistance, immune interactions, and virulence
RB Williams, MC Lorenz - MBio, 2020 - Am Soc Microbiol
The phagocytic cells of the innate immune system are an essential first line of antimicrobial
defense, and yet Candida albicans, one of the most problematic fungal pathogens, is …
defense, and yet Candida albicans, one of the most problematic fungal pathogens, is …