Critical illness polyneuropathies (CIP) and myopathies (CIM) are common complications of
critical illness. Several weakness syndromes are summarized under the term intensive care …

Cushing's syndrome (CS) patients have increased mortality primarily due to cardiovascular
events induced by glucocorticoid (GC) excess-related severe metabolic changes. Glucose …

Dexamethasone is widely used as an immunosuppressive therapy and recently as COVID-
19 treatment. Here, we demonstrate that dexamethasone sensitizes to ferroptosis, a form of …

Skeletal muscle atrophy is prevalent in a myriad of pathological conditions, such as
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …

Glucocorticoids are widely used for their unsurpassed anti-inflammatory and
immunomodulatory effects. However, the therapeutic use of glucocorticoids is almost always …

Glucocorticoids are known to regulate protein metabolism in skeletal muscle, producing a
catabolic effect that is opposite that of insulin. In many catabolic diseases, such as sepsis …

Glucocorticoid-induced myopathy is the most common type of drug-induced myopathy.
Nearly 60% of patients with Cushing's syndrome have muscle weakness. Glucocorticoid …

Cushing's syndrome (CS) is a severe condition that results from chronic exposure to
elevated circulating cortisol levels; it is a rare but potentially life-threating condition …

Glucocorticoids (GCs) are highly effective in the treatment of inflammatory and autoimmune
conditions but their therapeutic use is limited by numerous adverse effects. Recent insights …

Advanced cancer patients exhibit cachexia, a condition characterized by a significant
reduction in the body weight predominantly from loss of skeletal muscle and adipose tissue …