Type 2 chronic inflammatory diseases: targets, therapies and unmet needs
Over the past two decades, significant progress in understanding of the pathogenesis of type
2 chronic inflammatory diseases has enabled the identification of compounds for more than …
2 chronic inflammatory diseases has enabled the identification of compounds for more than …
The IL-4, IL-13 and IL-31 pathways in atopic dermatitis
C Dubin, E Del Duca… - Expert review of clinical …, 2021 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is the most common inflammatory skin disease. It has a
complex pathophysiology, with a combination of immune dysregulation and intrinsic barrier …
complex pathophysiology, with a combination of immune dysregulation and intrinsic barrier …
[HTML][HTML] Neuroimmune communication regulating pruritus in atopic dermatitis
Atopic dermatitis (AD) is a common, chronic-relapsing inflammatory skin disease with
significant disease burden. Genetic and environmental trigger factors contribute to AD …
significant disease burden. Genetic and environmental trigger factors contribute to AD …
Pruritus as a distinctive feature of type 2 inflammation
S Garcovich, M Maurelli, P Gisondi, K Peris… - Vaccines, 2021 - mdpi.com
Pruritus is a common symptom of several skin diseases, both inflammatory and neoplastic.
Pruritus might have a tremendous impact on patients' quality of life and strongly interfere …
Pruritus might have a tremendous impact on patients' quality of life and strongly interfere …
[HTML][HTML] Attenuating the atopic march: meta-analysis of the dupilumab atopic dermatitis database for incident allergic events
BACKGROUND Atopic march refers to the sequential development of allergic diseases from
infancy through adolescence, typically beginning with atopic dermatitis (AD) followed by …
infancy through adolescence, typically beginning with atopic dermatitis (AD) followed by …
The hidden sentinel of the skin: An overview on the role of interleukin-13 in atopic dermatitis
M Napolitano, F di Vico, A Ruggiero… - Frontiers in …, 2023 - frontiersin.org
Recent evidence suggests that interleukin (IL)-13 is a crucial cytokine involved in the
pathogenesis of atopic dermatitis (AD). It is a central driver of type-2 T-helper inflammation …
pathogenesis of atopic dermatitis (AD). It is a central driver of type-2 T-helper inflammation …
Cellular activation pathways and interaction networks in vascularized composite allotransplantation
Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive
surgery that has revolutionized the treatment of patients with devastating injuries, including …
surgery that has revolutionized the treatment of patients with devastating injuries, including …
Oral administration of Faecalibacterium prausnitzii and Akkermansia muciniphila strains from humans improves atopic dermatitis symptoms in DNCB induced NC …
Y Lee, HR Byeon, SY Jang, MG Hong, D Kim, D Lee… - Scientific Reports, 2022 - nature.com
Atopic dermatitis (AD) is a common inflammatory skin disease, and its pathogenesis is
closely associated with microbial homeostasis in the gut, namely the gut-skin axis …
closely associated with microbial homeostasis in the gut, namely the gut-skin axis …
The implications of pruritogens in the pathogenesis of atopic dermatitis
LS Wong, YT Yen, CH Lee - International journal of molecular sciences, 2021 - mdpi.com
Atopic dermatitis (AD) is a prototypic inflammatory disease that presents with intense itching.
The pathophysiology of AD is multifactorial, involving environmental factors, genetic …
The pathophysiology of AD is multifactorial, involving environmental factors, genetic …
[HTML][HTML] In vitro disease models for understanding psoriasis and atopic dermatitis
R Sarama, PK Matharu, Y Abduldaiem… - … in Bioengineering and …, 2022 - frontiersin.org
Psoriasis (PS) and Atopic Dermatitis (AD) are two of the most prevalent and misunderstood
inflammatory skin diseases. Dysregulations in the immune response are believed to play a …
inflammatory skin diseases. Dysregulations in the immune response are believed to play a …